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dementia

Featured Genetics Neurology Neuroscience

·May 26, 2026·10 min read

Gene Therapy Proven to Shield Brain from TDP-43 Damage

An experimental gene therapy called SynCav1 can protect the central nervous system from the cognitive decline linked to TDP-43-related proteinopathy, a primary driver of FTD, ALS, and over half of all Alzheimer’s cases.

Featured Neurology Neuroscience

·May 26, 2026·11 min read

Estrogen Loss May Drive Female Alzheimer’s

Post-menopausal estrogen loss triggers an environmental collapse in the "extracellular matrix" (ECM), the long-overlooked molecular scaffold that fills 20% of the brain's volume and regulates cellular communication within the hippocampus.

Featured Neurology Neuroscience

·May 22, 2026·9 min read

Heart Attacks Release Toxin That Damages Brain Function

Why do heart attacks so frequently trigger severe depression, anxiety, and accelerated dementia? A new study maps the "heart-brain axis," proving that dying cardiac tissue releases a toxic metabolic byproduct called methylglyoxal (MG).

Featured Neurology Neuroscience

·May 21, 2026·7 min read

Broken Sleep Rhythms: The Glymphatic Link to Dementia

During non-REM sleep, synchronized chemical waves trigger rhythmic vascular movements known as vasomotion, pumping cerebrospinal fluid through the glymphatic system to flush out toxic amyloid-beta and tau proteins. When these rhythms are fractured by psychiatric, cardiovascular, or age-related stressors, waste clearance stalls.

Featured Neurology Neuroscience

·May 20, 2026·8 min read

Healthy Weight and Quitting Smoking Reduce Dementia Risk

Can the metabolic consequences of quitting smoking cancel out its long-term benefits for the human brain? A new longitudinal study establishes a powerful link between smoking cessation and a 16% reduction in dementia risk.

This AI illustration shows brains on a plastic slide.

Featured Neurology Neuroscience

·May 18, 2026·8 min read

Connected Biochip Tracks How Diabetes Triggers Dementia

A new study launched the GlucoBrain project, a multi-disciplinary initiative to build a first-of-its-kind "organ-on-chip" device that bridges the gut, pancreas, and brain.

Featured Neurology Neuroscience

·May 18, 2026·9 min read

Brain Switch for Recent Memory Retrieval Identified

Neuroscientists identifies a specific "neural switch" that actively selects recent memories over past experiences.

Featured Neurology Neuroscience

·May 17, 2026·8 min read

Low-Level Air Pollution Linked to Cognitive Decline, Brain Damage

Can breathing everyday air quietly damage your brain structure decades before cognitive symptoms appear? A new study reveals that long-term exposure to low levels of air pollution is directly linked to worse memory, comprehension, and processing speed.

Featured Neurology Neuroscience

·May 16, 2026·8 min read

Overall Brain Health Protects Memory From Early Alzheimer’s

Why do some brains withstand the earliest onslaught of Alzheimer’s disease without showing cognitive decline? A new study demonstrates that maintaining good overall brain health can actively defend memory, attention, and executive function from early Alzheimer’s-related pathology.

This shows an older woman sleeping and microglia.

Featured Neurology Neuroscience

·May 12, 2026·6 min read

Targeting Brain “Clean-up” Cells to Fight Dementia

Researchers discovered that dysregulated circadian rhythms cause microglia, the brain’s immune cells, to become "stress-primed" and malfunction. This state prevents them from clearing amyloid plaques, accelerating dementia risk. Now, using DARI seedling grants, Souza is testing a stem-cell-derived "EV therapy" designed to keep these cells healthy and prevent neuroinflammation.

This shows the outline of two people and brains.

Featured Neurology Neuroscience

·May 9, 2026·8 min read

Reducing Visceral Fat Protects the Brain for Decades

A landmark 16-year MRI study identified cumulative abdominal fat as a specific, modifiable risk factor for brain atrophy. The findings demonstrate that sustained reductions in visceral fat, mediated by better glucose control, are essential for preserving hippocampal volume and cognitive function in late midlife, independent of total weight loss.