High-fat diets promote early inflammatory responses in the brain via an immune pathway associated with diabetes and neurodegenerative diseases. The findings suggest a link between metabolic dysfunction and cognitive impairment.
Machine learning algorithms can effectively recognize patterns in a patient's neuroimaging data that are specific to rare forms of dementia, allowing for early diagnosis and monitoring of disease progression.
Researchers report six minutes of high-intensity exercise on a regular basis can slow brain aging and delay the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. High-intensity exercise increases the production of BDNF, a protein implicated in memory, learning, and brain plasticity, which could protect the brain from age-related cognitive decline.
Gene usage in the brains of those who suffered severe COVID-19 infections was similar to that observed in the aging brain. Researchers say COVID-19 is associated with molecular signatures of brain aging.
Previous TBI increased the risk of frontotemporal dementia in those without a genetic risk factor for FTD. Additionally, researchers found those with FTD tend to be less educated than those with Alzheimer's disease.