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dementia

This shows a child and parent walking in a "forest" of DNA.

Featured Genetics Neurology Neuroscience

·December 4, 2025·7 min read

Mutation in Key Enzyme Triggers Ferroptosis and Childhood Dementia

Researchers have identified how a single mutation in the GPX4 enzyme causes neurons to undergo ferroptosis, leading to severe early-onset dementia. The study provides the first molecular evidence that ferroptosis can directly drive neurodegeneration in the human brain.

Featured Neurology Neuroscience

·December 2, 2025·6 min read

Obesity Speeds Alzheimer’s Biomarker by Up to 95 Percent

New longitudinal research shows that Alzheimer’s disease blood biomarkers rise up to 95 percent faster in people with obesity than in those without. While baseline tests initially appeared lower due to blood dilution, long-term tracking revealed a significantly accelerated buildup of neurodegeneration and amyloid pathology.

This shows an older woman getting a vaccine.

Neuroscience

·December 2, 2025·12 min read

Shingles Vaccine Linked to 20% Lower Dementia Risk

A large population analysis found that older adults who received the shingles vaccine were significantly less likely to develop dementia over the following seven years. The study exploited a rare age-based rollout policy that closely mimicked a randomized trial, allowing researchers to isolate the vaccine’s true effect.

Featured Neurology Neuroscience

·November 29, 2025·6 min read

The Way You Drive Might Signal Mild Cognitive Impairment

Researchers found that long-term driving behavior can reveal early signs of cognitive decline years before clinical diagnosis. Older adults who later developed impairment showed gradual reductions in trip frequency, night driving, and route variety compared to cognitively healthy peers.

This shows the outline of a person and a brain.

Featured Neurology Neuroscience

·November 24, 2025·8 min read

One in Two Americans Have Neurological Disorders

A comprehensive national analysis shows that over 180 million Americans—more than half the U.S. population—are living with a neurological disease or disorder. These conditions span the lifespan, from neurodevelopmental disorders to migraines to age-related diseases such as Parkinson’s and Alzheimer’s.

Featured Genetics Neurology Neuroscience

·November 21, 2025·6 min read

Genetics Plus Heart Health Markers Sharpen Dementia Risk

New research shows that dementia risk is best predicted by combining genetic vulnerability with cardiovascular disease markers, revealing a more precise and actionable way to identify who is most likely to develop the condition. While genes such as APOE4 and family history contribute heavily, equally powerful are modifiable factors like hypertension, obesity, and diabetes.

This shows a head, a brain, and supplement pills.

Featured Neurology Neuroscience

·November 21, 2025·6 min read

Supplement Shows Promise in Blocking Amyloid in Alzheimer’s

A new study shows that oral arginine, a naturally occurring amino acid, can significantly suppress amyloid-β aggregation in Alzheimer’s disease models. Researchers found that arginine not only prevented Aβ42 from clumping but also reduced plaques and inflammation in mouse and fruit fly models carrying Alzheimer’s-related mutations.

Featured Neurology Neuroscience

·November 19, 2025·7 min read

Lithium Fails to Slow Cognitive Decline in Alzheimer’s

A new meta-analysis of six randomized controlled trials shows that lithium supplementation does not significantly slow cognitive decline in people with mild cognitive impairment or Alzheimer’s disease. While preclinical evidence suggests lithium supports resilience against amyloid and tau pathology, these benefits failed to translate to clinical outcomes using traditional lithium salts.

Featured Neurology Neuroscience Visual Neuroscience

·November 12, 2025·5 min read

Low Income, Vision Loss, and Isolation Drive Dementia Risk

A new study reveals that people with lower incomes and those from historically underrepresented racial and ethnic groups carry a higher burden of modifiable dementia risk factors. Vision loss and social isolation were among the most significant contributors for those living below the poverty line, suggesting that better access to healthcare and community support could have major protective effects.

Featured Neurology Neuroscience

·November 12, 2025·5 min read

Speaking Multiple Languages May Slow Down Biological Aging

A large-scale study of more than 86,000 Europeans found that speaking multiple languages may help slow biological and cognitive aging. Using artificial intelligence to assess “biobehavioral age gaps,” researchers discovered that multilingual individuals were over twice as likely to show signs of healthy aging compared to monolinguals.

Featured Neurology Neuroscience Psychology

·November 11, 2025·7 min read

Stress Undermines Brain Circulation, Increases Dementia Risk

Researchers found that a rare class of neurons—type-one nNOS neurons—plays a central role in regulating brain blood flow and coordinating neural activity in mice. Removing these stress-vulnerable cells caused major drops in vessel oscillations and widespread reductions in electrical signaling, suggesting a crucial link between neuron loss, blood-flow decline, and brain-function impairment.

Featured Neurology Neuroscience

·November 5, 2025·6 min read

Your Neighborhood Could Influence Your Risk of Dementia

Researchers found that living in a socioeconomically deprived neighborhood can harm brain health as early as midlife. People from these areas showed more signs of small-vessel brain damage, slower thinking skills, and poorer control of lifestyle factors such as blood pressure, obesity, and sleep.