When treated with estrogen, mouse models showed marked reductions in inflammatory markers and a decrease in delirium-like behaviors.
Brain cells exposed to blood taken from COVID-19 patients with delirium showed a decrease in neurogenesis and an increase in cell death. The findings also indicate a key role for cytokines produced in the immune system during infection and shed light on the molecular mechanisms of COVID-19 related delirium.
A newly developed artificial intelligence algorithm can accurately and reliably assess unconsciousness in patients under anesthesia based on brain activity.
Artificially inducing peripheral inflammation in mice triggered the sudden onset of delirium-like cognitive dysfunction, and this was mediated by a disturbance in energy metabolism.
Coronavirus infection can lead to an array of neurological complications, including delirium, stroke, and a rare, often fatal neuroinflammatory condition called ADEM. The neurological complications did not always correlate with the severity of respiratory symptoms. In some patients, brain inflammation was likely caused by an immune response to COVID-19, suggesting the neurological damage may be a result of immune system activation rather than the virus itself.
Computerized language analysis reveals linguistic markers of depression were found in Poe's personal letters and professional writing, but none are consistent with suicidal ideations.
A new study reports delirium can accelerate cognitive decline in people undergoing pathological changes associated with dementia.
According to researchers, some common antibiotics could be linked to delirium and some other temporary brain problems.
Researchers report of accelerated cognitive decline in Alzheimer's disease patient who also exhibit signs of delirium.
A new study explores the connection between mechanical ventilation and hippocampal damage in ICU patients.
