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Featured Neuroscience Open Neuroscience Articles

·March 27, 2022·5 min read

Scientists Hunt for Neurons Responsible for Alcohol Withdrawal

Researchers reveal the role corticotropin-releasing factor produced by neurons plays in alcohol withdrawal symptoms.

Featured Neuroscience Psychology

·June 5, 2020·5 min read

Chemical messenger in brain could point to better treatments for anxiety

Corticotropin-releasing factor and neuropeptide Y work in synchronized opposition to each other to remodel and rewire neurons in the amygdala as a response to stress. The process, researchers say, can be manually reversed to help relieve anxiety.

Featured Neuroscience Psychology

·March 14, 2020·5 min read

How chronic stress changes the brain, and what you can do to reverse the damage

Chronic stress can affect a person's health and mental well being. Due to the COVID-19 virus, chronic stress is on the rise worldwide. Researchers examine the general and psychological health implications of chronic stress and suggest some methods we can adopt to keep our stress levels in check.

Featured Neuroscience Psychology

·March 2, 2020·2 min read

Coping strategies, a matter of neuron

Researchers uncover a key role of medial prefrontal cortex corticotropin-releasing factor interneurons for bidirectionally controlling motivated behavioral styles under stress. The findings could help in the development of new treatments for PTSD.

Electrophysiology Featured Neurology Neuroscience Pain Psychology

·September 26, 2019·4 min read

Molecular link between chronic pain and depression revealed

Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.

Featured Neuroscience Open Neuroscience Articles

·March 18, 2019·5 min read

Scientists hunt down the brain circuit responsible for alcohol cravings

Optogenetic inactivation of CRF neurons in the central nucleus of the amygdala decreases escalation of alcohol consumption and intensity of withdrawal in rodent models of alcoholism. The findings suggest a potential target for treating excessive drinking in alcohol use disorder.