3,6’-dithiopomalidomide (DP), an anti-inflammatory drug candidate, protected mouse models of Alzheimer's disease against cognitive decline by reducing neuroinflammation.
Young people who experience high blood pressure may have an increased risk of brain changes during mid-life that are associated with later cognitive decline.
Identifying the optimal number of individual treatment sessions for those with cognitive decline associated with dementia is crucial for managing the neurodegenerative disease.
Study establishes a robust link between ozone exposure and an increase in cognitive impairment in older adults.
Researchers have identified a link between misshapen, fast replicating tau proteins, and accelerated cognitive decline. The findings shed new light on the development and progression of Alzheimer's disease.
Researchers have identified a "sweet spot" during exercise that appears to reverse age-related cognitive decline and improves learning in mouse models.
Work plays an active role in keeping the brain healthy and retaining cognitive abilities as we age, researchers report.
Older people who experience elevated heart rates are at increased risk for developing dementia, researchers report.
Physical activity appears to reduce microglial activation and improve cognition in the aging human brain, researchers report.
A new framework reveals Alzheimer's disease is far more complex than previously believed. Rather than being a disease where the same causes produce the same outcomes, researchers found three different models for the disease, each with its own characterizations and dynamics.
Older adults who sleep less than 4.5 hours, or more than 6.5 hours per night and who experience sleep disruptions are at greater risk of cognitive decline, researchers report.
In both aging human and mouse experiments, researchers identified a link between the MEF2 gene and cognitive resilience. Findings suggest enhancing MEF2 activity could protect the brain against age-related dementia.
