CJD

the synthetic prion is shown

First Artificial Human Prion Created

Neuroscience NewsJune 6, 2018

Researchers have successfully created a synthetic version of a human prion, a protein associated with brain wasting diseases like sporadic Creutzfeldt-Jakob disease. The prions may help shed new light on, and provide treatment options, for those with CJD and other prion related diseases.... Read More...

FeaturedGeneticsNeurologyneurotechOpen Neuroscience Articles6 min read

Image shows a brain of a CJD patient.

Prion Protein in Skin of CJD Patients

Neuroscience NewsNovember 22, 2017

Researchers have detected a prion protein associated with CJD on the skin of almost two dozen people who died from the disease. The findings raise questions as to whether transmission of the disease via skin transplantation may be possible, and whether a simple skin test could detect the disease.... Read More...

FeaturedNeurology7 min read

Image shows alpha-synuclein amyloid fibrils.

Molecular Link Between Parkinson’s and Prion Diseases Discovered

Neuroscience NewsSeptember 14, 2017

Researchers detail the complex interaction between alpha synuclein and the prion protein PrPc.... Read More...

FeaturedNeurologyOpen Neuroscience Articles4 min read

Image shows a schwannoma tumor cell.

Research Offers Hope For NF2 Neuro-Tumor Patients

Neuroscience NewsJuly 10, 2017

Researchers from the University of Plymouth have discovered the tole PrPC plays in the development of neurofibromatosis 2 tumors. According to the study, the prion protein is overproduced in schwannomas, compared with healthy Schwann cells. This overproduction is a result of Merlin deficiency and contributed to tumor growth in NF2 patients.... Read More...

Brain CancerFeaturedGeneticsNeurology7 min read

Image shows prions.

Gut Cells Are Gatekeepers For Infectious Brain Diseases

Neuroscience NewsDecember 14, 2016

A new study reports M cells found in the lining of the gut can help to protect the against prion infections.... Read More...

FeaturedNeurologyOpen Neuroscience Articles5 min read

Image shows a fruit fly.

Fruit Fly Model of Brain Disease Could Lead to Blood Test for vCJD

Neuroscience NewsOctober 14, 2016

A new fruit fly model in development could lead to low cost blood tests to help diagnose a deadly prion disease.... Read More...

FeaturedNeurologyNeuroscience7 min read

Image shows stained brain slice for alpha synuclein.

Caffeine Based Compounds Show Promise Against Parkinson’s

Neuroscience NewsSeptember 30, 2016

Researchers have developed two caffeine based compounds that show promise in the fight against Parkinson's disease.... Read More...

FeaturedNeurology5 min read

Image shows the architecture of a prion.

Newly Deciphered Structure Suggests How Infectious Prions Replicate

Neuroscience NewsSeptember 11, 2016

Researchers have uncovered the 3D structure of infectious prions.... Read More...

FeaturedNeurologyOpen Neuroscience Articles7 min read

Image shows healthy axons.

Beneficial Role Clarified for Brain Protein Associated with Mad Cow Disease

Neuroscience NewsAugust 8, 2016

Researchers report a protein normally associated with prion diseases may help to maintain myelin.... Read More...

FeaturedNeurology6 min read

Image shows prions.

Improved Detection for Deadly Prion Diseases

Neuroscience NewsApril 8, 2016

A new assay offers improved sensitivity of current tests for transmissible spongiform encephalopathies, researchers report.... Read More...

FeaturedNeurology6 min read

Image shows the 3d structure of a prion.

Benefits and Toxicity of Anti-Prion Antibodies in the Brain

Neuroscience NewsJanuary 28, 2016

A new study looks at the toxicity and benefits of the use of anti-prion antibodies.... Read More...

FeaturedNeurology5 min read

Image shows amyloid beta in the cerebral cortex.

Alzheimer-Type Brain Pathology Following Transplantation of Dura Mater

Neuroscience NewsJanuary 26, 2016

Researchers have discovered Alzheimer-type pathology in the brains of some dura mater transplant recipients who later died of CJD.... Read More...

FeaturedNeurologyOpen Neuroscience Articles3 min read