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          CJD

          This shows a brain
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·October 19, 2021·4 min read

          Viral Infections Could Promote Neurodegeneration

          Some viral infections could increase intercellular spreading of protein aggregates associated with neurodegenerative disorders, increasing the risk for developing Alzheimer's, Parkinson's, and other neurodegenerative diseases.
          Read More
          This shows a diagram of a prion protein
          FeaturedNeuroscience
          ·August 28, 2021·4 min read

          First Atomic-Level Imaging of Lethal Prions Provide Sharpened Focus for Potential Treatments

          Cryogenic-electron microscopy allowed researchers to determine the basic building blocks of prion proteins, including the placements of their amino acids.
          Read More
          FeaturedNeurologyNeuroscience
          ·March 15, 2021·3 min read

          Crucial Step in Formation of Deadly Brain Diseases Discovered

          Study sheds light on what causes normal proteins to convert to a diseased form associated with CJD and Kuru.
          Read More
          tau buildup in brain slices
          FeaturedGeneticsNeurologyNeuroscience
          ·May 1, 2019·9 min read

          Alzheimer’s disease is a ‘double-prion disorder’

          Self-propagating amyloid and tau act as prions in the pathology of Alzheimer's disease. Higher levels of the prions in human brain samples were strongly correlated with early onset of Alzheimer's and death at a younger age.
          Read More
          skin samples
          FeaturedNeurologyOpen Neuroscience Articles
          ·January 22, 2019·5 min read

          Skin Test Detects Prion Infection Before Symptoms Appear

          Researchers have developed a new skin biopsy test that can detect prion infections in skin samples before symptoms of disease appear.
          Read More
          hippocampal slices
          FeaturedNeurologyNeuroscience
          ·December 14, 2018·6 min read

          Alzheimer’s Protein Accidentally Transmitted to Patients Via Discontinued Medical Treatments

          Researchers report human growth hormone, prepared from human tissue prior to 1985, may have been contaminated with seeds of the amyloid beta protein. In a new study, researchers injected mice with the original c-hGH batches containing amyloid beta which seeded amyloid pathology, even decades after storage. Findings support the hypothesis that the Alzheimer's causing proteins can be transmitted to from contaminated materials.
          Read More
          the synthetic prion is shown
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·June 6, 2018·5 min read

          First Artificial Human Prion Created

          Researchers have successfully created a synthetic version of a human prion, a protein associated with brain wasting diseases like sporadic Creutzfeldt-Jakob disease. The prions may help shed new light on, and provide treatment options, for those with CJD and other prion related diseases.
          Read More
          Image shows a brain of a CJD patient.
          FeaturedNeurology
          ·November 22, 2017·5 min read

          Prion Protein in Skin of CJD Patients

          Researchers have detected a prion protein associated with CJD on the skin of almost two dozen people who died from the disease. The findings raise questions as to whether transmission of the disease via skin transplantation may be possible, and whether a simple skin test could detect the disease.
          Read More
          Image shows alpha-synuclein amyloid fibrils.
          FeaturedNeurologyOpen Neuroscience Articles
          ·September 14, 2017·3 min read

          Molecular Link Between Parkinson’s and Prion Diseases Discovered

          Researchers detail the complex interaction between alpha synuclein and the prion protein PrPc.
          Read More
          Image shows a schwannoma tumor cell.
          Brain CancerFeaturedGeneticsNeurology
          ·July 10, 2017·6 min read

          Research Offers Hope For NF2 Neuro-Tumor Patients

          Researchers from the University of Plymouth have discovered the tole PrPC plays in the development of neurofibromatosis 2 tumors. According to the study, the prion protein is overproduced in schwannomas, compared with healthy Schwann cells. This overproduction is a result of Merlin deficiency and contributed to tumor growth in NF2 patients.
          Read More
          Image shows prions.
          FeaturedNeurologyOpen Neuroscience Articles
          ·December 14, 2016·4 min read

          Gut Cells Are Gatekeepers For Infectious Brain Diseases

          A new study reports M cells found in the lining of the gut can help to protect the against prion infections.
          Read More
          Image shows a fruit fly.
          FeaturedNeurologyNeuroscience
          ·October 14, 2016·5 min read

          Fruit Fly Model of Brain Disease Could Lead to Blood Test for vCJD

          A new fruit fly model in development could lead to low cost blood tests to help diagnose a deadly prion disease.
          Read More
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          This shows two heads.

          Untangling the Human Mind: The Interplay Between Cognition and Personality

          This shows two women drinking.

          Empathy’s Influence on Drinking Patterns

          This shows a sleeping man.

          Sleep Apnea and Its Link to Alzheimer’s Associated Brain Changes

          This shows a woman covered in leaves.

          Getting the Skinny on Cannabis Use: The Effect of Cannabis on Weight and Metabolism

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