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choroid plexus

·September 13, 2022·6 min read

Preventing ‘Chemo Brain’ With Antioxidants Targeting the Spinal Fluid

Using gene editing to boost the production of SOD3 in the choroid plexus reduced oxidative damage to brain tissue and cerebral spinal fluid in mice exposed to methotrexate.

Featured Neurology Neuroscience

·May 17, 2022·5 min read

Choroid Plexus Volume Linked to Alzheimer’s Disease

A new study reports that increased volume in the choroid plexus appears to be associated with greater cognitive impairment and Alzheimer's disease.

Featured Neuroscience Psychology

·October 21, 2021·2 min read

Gut-Brain Axis Response to Inflammation May Underlie Inflammatory Bowel Disease-Related Mental Symptoms

The vascular barrier in the choroid plexus locks down access to the brain in response to gut inflammation that causes IBD. The dysregulated activity of the gut-brain vascular axis appears to protect the brain from inflammation. However, the mechanism may increase the risk of both cognitive and mental health problems associated with IBD.

This shows the choroid plexus of a mouse

Featured Neurology Neuroscience Open Neuroscience Articles

·July 11, 2021·4 min read

Immaturity of Microbiota and Epithelial Barriers Implicated in Neonatal Meningitis

Immaturity of the gut microbiome and epithelial barriers in the gut and choroid plexus appear to play a significant role in neonatal susceptibility to meningitis.

This shows immune cells in the choroid plexus

Featured Genetics Neuroscience

·October 9, 2020·5 min read

The Choroid Plexus: A Conduit for Prenatal Inflammation?

Mouse study reveals the choroid plexus can act as a conduit for inflammation that can arise from maternal inflammation, impacting fetal brain development.

Featured Neurology Neuroscience

·February 5, 2020·3 min read

Activating immune cells could revitalize the aging brain

Activating group 2 innate lymphoid cells in aging brains helps improve memory in mice. The findings could help in the development of treatments for neurodegenerative diseases associated with aging.

This shows the outline of two heads and neurons

Featured Genetics Neurology Neuroscience

·May 6, 2019·3 min read

Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders

Using mouse models, researchers have developed a comprehensive map of the brain's immune cells. The study found microglia in the choroid plexus showed a similar activation state as microglia that come into contact with Amyloid deposits.

brain scans of a man with severe brain calcifications

Featured Neurology Neuroscience Open Neuroscience Articles

·June 12, 2018·4 min read

Smoking and Diabetes Linked to Brain Calcifications

Researchers report people who are diabetic or who smoke are more likely to have calcification in the hippocampus. The study hypothesized hippocampal calcification may contribute to cognitive deterioration and brain atrophy.