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          chemotherapy

          This shows a head covered by fog.
          Brain CancerFeaturedNeurologyNeuroscience
          ·May 13, 2025·7 min read

          CAR-T Brain Fog Mirrors Chemo and COVID

          Patients receiving CAR-T cell therapy often report brain fog, and new research shows this cognitive impairment stems from the therapy itself, not just the cancer or other treatments. A mouse study revealed that CAR-T-induced immune responses activate brain microglia, triggering inflammation that damages myelin-producing cells, reducing signal efficiency in the brain.
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          This shows two heads and brains.
          Brain CancerFeaturedNeurologyNeuroscience
          ·April 9, 2025·3 min read

          Chemotherapy Disrupts Brain Connectivity

          New research reveals that chemotherapy can lead to rapid and widespread changes in brain connectivity in breast cancer patients. Using functional MRI scans, scientists observed disruptions in the frontal-limbic system and cerebellar cortex, regions involved in executive function and memory.
          Read More
          This shows a woman exercising.
          Brain CancerFeaturedNeuroscience
          ·October 22, 2024·4 min read

          Exercise During Chemotherapy Boosts Cognitive Function

          A recent clinical trial found that women who began an aerobic exercise program during chemotherapy for breast cancer reported improved cognitive function and quality of life compared to those who received standard care. Participants in the exercise group felt they could better concentrate and remember things, helping to reduce the effects of "chemo-brain."
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          This shows a brain and violets.
          Brain CancerFeaturedNeurologyNeuroscience
          ·October 1, 2024·4 min read

          Violet Compound Boosts Chemo Effectiveness for Glioblastoma

          Scientists have discovered that a molecule called kalata B1, found in violets, can significantly enhance the effectiveness of the chemotherapy drug Temozolomide (TMZ) in treating glioblastoma. This synthetic molecule reduced the amount of TMZ required to kill cancer cells by over tenfold in lab tests. Researchers believe that the synthetic version of kalata B1, which mirrors the natural molecule’s structure, could be a potential breakthrough in glioblastoma treatment. While the discovery is promising, the team stresses that clinical trials are still far off.
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          This shows DNA.
          Brain CancerFeaturedGeneticsNeuroscience
          ·September 4, 2023·5 min read

          Two Key Genes Revealed in Chemotherapy Resistance

          Researchers identified two genes - NEK2 and INHBA - responsible for causing chemotherapy resistance in head and neck cancer patients. Remarkably, when these genes are silenced, previously resistant cancer cells begin responding to chemotherapy.
          Read More
          This shows a record player
          Brain CancerFeaturedNeuroscience
          ·March 22, 2023·3 min read

          Turn Up Your Favorite Song to Improve Medication Efficacy

          Listening to music may help boost the beneficial effects of medicine while helping to reduce some of the side effects. Cancer patients who listened to their favorite music while experiencing chemotherapy-related nausea reported a decrease in nausea severity and stress.
          Read More
          This shows a brain
          Brain CancerFeaturedNeuroscience
          ·February 28, 2023·6 min read

          Identifying the Inflammatory Cells Behind Chemo Brain

          Microglia appear to be associated with brain fog and memory problems that arise as a result of exposure to chemotherapy, researchers discovered. Deleting the immune cells from the microglia in mice who received the chemotherapy drug paclitaxel lowered inflammation and restored memory function.
          Read More
          This shows the outline of a head
          Brain CancerFeaturedNeuroscience
          ·November 16, 2022·8 min read

          Implanted Pump Safely Delivered Chemo Straight to the Brain in Patients With Brain Cancer

          A new implantable pump system safely and effectively bypasses the blood-brain barrier to deliver chemotherapy drugs to those with glioblastoma brain cancer.
          Read More
          This show a brain
          Brain CancerFeaturedNeuroscience
          ·September 13, 2022·6 min read

          Preventing ‘Chemo Brain’ With Antioxidants Targeting the Spinal Fluid

          Using gene editing to boost the production of SOD3 in the choroid plexus reduced oxidative damage to brain tissue and cerebral spinal fluid in mice exposed to methotrexate.
          Read More
          This shows a brain
          Brain CancerFeaturedNeuroscience
          ·September 2, 2022·5 min read

          Unlocking the Mystery of ”Chemo Brain”

          Researchers have uncovered the molecular mechanisms behind cognitive deficits and brain fog associated with chemotherapy, and identified a current FDA-approved drug for multiple sclerosis that can help reduce chemotherapy-induced cognitive impairments.
          Read More
          This shows the outline of a head
          Brain CancerFeaturedNeuroscience
          ·August 28, 2022·4 min read

          Neurofeedback Shows Promise for Addressing ‘Chemo Brain’

          Neurofeedback has the potential to alleviate symptoms of "brain fog" and cognitive impairments associated with chemotherapy.
          Read More
          This shows sperm and an egg
          Brain CancerFeaturedGeneticsNeuroscience
          ·May 13, 2022·7 min read

          Increased Mutations in Children Can Be Traced Back to Mistakes in Father’s Sperm

          Hypermutation in children may be linked to increased mutations in the sperm of the biological father, especially fathers who received certain forms of chemotherapy to treat cancer early in life.
          Read More
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          This shows a person drawing with both hands.

          Left-Handed Creativity Myth Debunked

          This shows a brain.

          Tiny RNA Mark Helps Explain Brain Wiring and Mental Disorders

          This shows a brain and musical notes.

          Brain Tracks Emotional Transitions Through Music

          This shows a person and chat bubbles.

          People Prefer Human Empathy, Even When AI Says the Same Thing

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