Study is first to show feasibility and efficacy of a new use for autologous stem cell transplant. For the first...
“We identified a subset of brain tumor cells that are slower growing or remain at rest, and appear to be the source of cancer recurrence after standard therapy in which the drug temozolomide is given to stop the tumor’s growth,” said Dr. Luis Parada. “Current therapy targets fast-growing tumor cells but not those responsible for new tumors. To the best of our knowledge, this is the first identification of a cancer stem-like cell in a spontaneously forming tumor inside a mammal.”
Researchers discovered a mutant form of Chk1 gene that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells.
A new study argues that prolonged chemotherapy decreases the development of new brain cells, and disrupts ongoing brain rhythms in the part of the brain responsible for making new memories.
Researchers confirm the mental fogginess produced as a result of taking the cancer drug tamoxifen, is real. They have also discovered an existing drug compound which appears to counteract the effects of this medication.
Brain cancer cells resist therapy by temporarily losing gene mutations targeted by drugs, but re-amplify the mutation once the treatments have stopped, a new study reports.
Patients who experience chemobrain after treatment for cancer show brain network disruptions, researchers report.
Recurrent gliomas could have genetic profiles which are different from those of the initial tumors that spawned them, a new study reports.
A new study provides a possible explanation as to what causes cognitive and memory problems associated with chemotherapy treatments.
Researchers suggest delivering chemotherapy directly into the brain cavity could offer a better way to treat tumors which have metastasized to the brain.
A new study reports human neural stem cells show promise for reversing cognitive impairments following chemotherapy.
Researchers report they might have discovered why some people are resistant to standard treatments for brain cancer, and it's in their DNA.
