Researchers identified a distinct population of GABAergic neurons activated by general anesthetic in the central amygdala of mice. The findings point to central amygdala GABAergic neurons as a potential therapeutic target to alleviate chronic pain.
A combination of chronic stress and high-calorie diets raised insulin levels tenfold in the amygdala of mice. Prolonged high levels of insulin in the central amygdala resulted in neurons becoming desensitized to insulin. The desensitized neurons boosted NPY levels, which promoted eating and reduced the normal homeostasis response to burn calories. The findings may shed light on why some indulge in high-calorie foods when stressed, and why this may lead to obesity.
Insulin signaling plays a role in regulating synaptic function, glucose homeostasis, and cognition, a new study reports. Impairments in insulin signaling result in metabolic defects, in addition to memory and learning deficits, mirroring the cognitive impairments associated with Alzheimer's disease.
Researchers have identified a specific circuit in the brain's central amygdala that raises anxiety levels. The study could pave the way for the development of new treatments for anxiety disorders.
Researchers have identified neurons in the amygdala that make food consumption rewarding. Activating NTR2a neurons caused mice to eat for longer periods of time.
According to a new study, alcohol increases neural activity in the central amygdala.
Neurons in an area of the brain commonly associated with fear drive pleasure seeking behaviors, a new study reports.
Using optogenetics to stimulate neurons in the central amygdala, researchers turn on predatory hunting motivation in mice.
