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          central amygdala

          This shows neurons
          FeaturedNeurologyNeurosciencePain
          ·May 18, 2020·4 min read

          Scientists find brain center that ‘profoundly’ shuts down pain

          Researchers identified a distinct population of GABAergic neurons activated by general anesthetic in the central amygdala of mice. The findings point to central amygdala GABAergic neurons as a potential therapeutic target to alleviate chronic pain.
          Read More
          This shows neurons in the central amygdala
          FeaturedNeuroscience
          ·April 25, 2019·4 min read

          Comfort food leads to more weight gain during stress

          A combination of chronic stress and high-calorie diets raised insulin levels tenfold in the amygdala of mice. Prolonged high levels of insulin in the central amygdala resulted in neurons becoming desensitized to insulin. The desensitized neurons boosted NPY levels, which promoted eating and reduced the normal homeostasis response to burn calories. The findings may shed light on why some indulge in high-calorie foods when stressed, and why this may lead to obesity.
          Read More
          PET brain scan of an alzheimer's patient
          FeaturedNeurologyNeuroscience
          ·March 14, 2019·4 min read

          Insulin Signaling Failures in the Brain Linked to Alzheimer’s Disease

          Insulin signaling plays a role in regulating synaptic function, glucose homeostasis, and cognition, a new study reports. Impairments in insulin signaling result in metabolic defects, in addition to memory and learning deficits, mirroring the cognitive impairments associated with Alzheimer's disease.
          Read More
          amygdala brain slice shown
          FeaturedNeuroscience
          ·May 29, 2018·3 min read

          How a Brain Circuit Generates Anxiety

          Researchers have identified a specific circuit in the brain's central amygdala that raises anxiety levels. The study could pave the way for the development of new treatments for anxiety disorders.
          Read More
          Image shows neurons.
          FeaturedNeuroscience
          ·August 22, 2017·5 min read

          Brain Region Mediates Pleasure of Eating

          Researchers have identified neurons in the amygdala that make food consumption rewarding. Activating NTR2a neurons caused mice to eat for longer periods of time.
          Read More
          Image shows the location of the amygdala in the brain.
          FeaturedNeuroscience
          ·April 12, 2017·4 min read

          Surprising Brain Change Appears to Drive Alcohol Dependence

          According to a new study, alcohol increases neural activity in the central amygdala.
          Read More
          Image shows a the BLA in the human brain.
          FeaturedNeurosciencePsychology
          ·March 23, 2017·5 min read

          Brain Circuit That Drives Pleasure Inducing Behavior Identified

          Neurons in an area of the brain commonly associated with fear drive pleasure seeking behaviors, a new study reports.
          Read More
          Image shows a mouse chasing a cricket.
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·January 12, 2017·4 min read

          Switching on the Predatory Kill Instinct in Mice

          Using optogenetics to stimulate neurons in the central amygdala, researchers turn on predatory hunting motivation in mice.
          Read More

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          This shows an older man.

          Chronic Stress and Depression Linked to Alzheimer’s Risk

          This shows two young children playing with blocks.

          Playful Brains: Early Years Play Shapes Children’s Futures

          This shows a woman sleeping.

          Sleep Struggles Link to Elevated Risk of Hypertension

          This shows a woman talking to her therapist.

          MDMA Makes People Feel More Connected During Conversations

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