A nuclear fragment protein activates Xkr4 to display an "eat me" signal to phagocytes.
TNFR1 receptors arrange themselves into clusters, joining together trimers and making oligomers that create a pro-inflammatory response observed in a variety of diseases.
Rather than having an equal chance of survival, cell death appears to be controlled by a mechanism that filters our the less fit cells.
New finding could lead to novel therapeutic approaches in the treatment of neurodegenerative diseases.
Researchers have identified a protein embedded in the surface of mitochondria that opens the door to cell death.
Researchers visualize the molecular changes in a critical cell death protein that force cells to die. Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions.
