Cryogenic-electron microscopy allowed researchers to determine the basic building blocks of prion proteins, including the placements of their amino acids.
Study reveals the surface features of human prions responsible for their replication in the brain. The findings provide a template to identify structurally important sites on other misfolded proteins, such as those associated with Alzheimer's disease.
A neuroimaging study of people with Down syndrome reveals subtle differences in the structure and function of the hippocampus.
A previously unknown gene and associated protein have been linked to the development of Alzheimer's disease. By suppressing the protein, named Aggergatin by the researchers, it may be possible to slow down or prevent the development of the neurodegenerative disease.
Researchers say the 4.5 million-year old fossil shows evidence of greater reliance on bipedalism than previously suggested.
Researchers have identified three regions in the genome where significant genetic differences between the sexes exist. These differences also varied by cancer type. The findings suggest specific genetic tests tailored to the different sexes could help assess cancer risks.
Researchers have successfully created a synthetic version of a human prion, a protein associated with brain wasting diseases like sporadic Creutzfeldt-Jakob disease. The prions may help shed new light on, and provide treatment options, for those with CJD and other prion related diseases.
Researchers have developed a new algorithm that integrates Alzheimer's indicators from MRI measurements to predict patients with the neurodegenerative disease.