Researchers have identified a link between misshapen, fast replicating tau proteins, and accelerated cognitive decline. The findings shed new light on the development and progression of Alzheimer's disease.
Study reveals the surface features of human prions responsible for their replication in the brain. The findings provide a template to identify structurally important sites on other misfolded proteins, such as those associated with Alzheimer's disease.
A previously unknown gene and associated protein have been linked to the development of Alzheimer's disease. By suppressing the protein, named Aggergatin by the researchers, it may be possible to slow down or prevent the development of the neurodegenerative disease.