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          CAR-t

          This shows a head covered by fog.
          Brain CancerFeaturedNeurologyNeuroscience
          ·May 13, 2025·7 min read

          CAR-T Brain Fog Mirrors Chemo and COVID

          Patients receiving CAR-T cell therapy often report brain fog, and new research shows this cognitive impairment stems from the therapy itself, not just the cancer or other treatments. A mouse study revealed that CAR-T-induced immune responses activate brain microglia, triggering inflammation that damages myelin-producing cells, reducing signal efficiency in the brain.
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          This shows the glioblastoma model.
          Brain CancerFeaturedNeurologyNeuroscience
          ·December 9, 2024·6 min read

          Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

          Glioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.
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          This is a glioblastoma tissue section.
          Brain CancerFeaturedNeurologyNeuroscience
          ·September 26, 2024·5 min read

          Novel CAR-T Therapy Shows Promise in Targeting Glioblastoma

          Researchers have developed a promising CAR-T cell therapy targeting glioblastoma, the most aggressive brain tumor. The therapy uses genetically modified T cells to target a specific marker on tumor cells, potentially overcoming the limitations of traditional treatments.
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          This shows neurons.
          Brain CancerFeaturedGeneticsNeurologyNeuroscience
          ·April 19, 2024·4 min read

          CAR-T Trial Targets Glioblastoma Brain Cancer

          Researchers initiated a pioneering clinical trial using an advanced form of CAR-T therapy, enhanced by synthetic notch (synNotch) technology, to treat glioblastoma. This trial represents a significant shift towards targeted, safer cancer therapies.
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          This shows brain scans.
          Brain CancerFeaturedNeurologyNeuroscience
          ·April 14, 2024·5 min read

          Revolutionizing Glioblastoma Treatment

          Researchers demonstrated significant initial success using CAR-T therapy for glioblastoma, a notoriously deadly brain cancer. They detailed the outcomes of the first three patients in a Phase 1 clinical trial who experienced dramatic tumor reductions shortly after treatment.
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          This shows a drawing of a t cell
          Brain CancerFeaturedNeuroscience
          ·December 11, 2022·4 min read

          CAR-T-Cell Shows Promise in Patients With Lymphoma of the Brain and Spinal Cord in Early Trial

          Axicabtagene ciloleucel (axi-cel), a form of CAR-T therapy appears to be safe and has encouraging signs of efficacy in treating both lymphoma of the brain and spinal cord injury.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·December 6, 2022·5 min read

          Immunotherapy Eliminates Disease-Causing Cells in Multiple Sclerosis-Like Disease

          CAR-T, a therapy generally used in the treatment of cancer, has been shown to eliminate unhealthy cells that trigger autoimmunity in mouse models of multiple-sclerosis.
          Read More
          brain
          Brain CancerFeaturedNeurology
          ·April 16, 2018·8 min read

          Altered Immune Cells Clear Childhood Brain Tumor: Mouse Study

          A fatal brain stem tumor was cleared by injecting it with engineered T-cells that recognized cancer and targeted it for destruction in mouse models, researchers report.
          Read More

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          This shows a brain.

          Genetic Roots of Depression Reveal Strong Suicide Risk Signals

          This shows the outline of people and speech bubbles.

          Why Sharing Good Deeds Feels Bad

          This shows a brain and a gut.

          No Evidence the Gut Microbiome Causes Autism

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          Why Women Face Worse Long COVID

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