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Cancer

Brain Cancer Featured Neurology Neuroscience

·December 12, 2024·8 min read

Glioblastoma Syncs With the Body’s Internal Clock

Glioblastoma, an aggressive brain cancer, syncs its internal clock to the host’s circadian rhythms, leveraging daily hormone cycles for growth. Blocking these signals slowed tumor progression in mice and revealed that the timing of treatments like dexamethasone (DEX) critically influences outcomes.

Brain Cancer Featured Neurology Neuroscience

·December 9, 2024·6 min read

Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

Glioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.

Brain Cancer Featured Neuroscience

·December 7, 2024·5 min read

Ketogenic Diet Enhances CAR-T Cancer Therapy

Researchers have found that a ketogenic diet boosts CAR T cell therapy effectiveness by enhancing tumor control and survival in mice with lymphoma. The key is beta-hydroxybutyrate (BHB), a metabolite produced during ketosis, which CAR T cells prefer as an energy source over glucose. Laboratory models showed that BHB supplementation led to complete cancer remission in most mice and enhanced CAR T cell expansion.

Brain Cancer Featured Neurology Neuroscience

·December 6, 2024·7 min read

Targeted Immune Cells Destroy Brain Tumors

Researchers have created a "molecular GPS" to guide immune cells directly to the brain, enabling precise targeting of tumors like glioblastoma. These cells use a unique protein code to navigate and attack cancer while sparing healthy tissue, offering a safer alternative to traditional treatments. In mice, this technology successfully cleared tumors, prevented recurrences, and reduced brain inflammation in models of multiple sclerosis.

Brain Cancer Featured Neurology Neuroscience

·November 20, 2024·6 min read

AI Improves Brain Tumor Detection

AI models trained on MRI data can now distinguish brain tumors from healthy tissue with high accuracy, nearing human performance. Using convolutional neural networks and transfer learning from tasks like camouflage detection, researchers improved the models’ ability to recognize tumors.

Featured Genetics Neuroscience

·November 15, 2024·6 min read

Cannabis Use Linked to Epigenetic Changes, Cancer Risk

Research indicates that cannabis use causes cellular damage that increases the risk of highly cancerous tumors by disrupting mitochondria and damaging DNA. This genotoxicity can result in mutations, accelerated aging, and birth defects, with potential to be passed on to future generations through egg and sperm. Insights from broader mitochondrial research provide a mechanistic understanding of how cannabis affects genetic stability.

Brain Cancer Featured Neurology Neuroscience

·November 12, 2024·5 min read

CAR T-Cell Therapy Recruits Brain’s Defenses Against Glioblastoma

Researchers have developed an innovative CAR T-cell therapy to combat glioblastoma, the most common malignant brain tumor in adults. This approach not only attacks tumor cells directly but also reprograms the tumor's microenvironment, enabling immune cells to fight the cancer rather than protect it.

This shows a doctor looking at brain scans.

Brain Cancer Featured Neurology Neuroscience

·November 7, 2024·4 min read

Novel Vaccine Targets Deadly Brain Tumors with Precision

A novel vaccine can mobilize the immune system to precisely target and attack cancerous brain tumors, specifically gliomas, one of the deadliest brain tumor types. This groundbreaking work demonstrates that the body’s immune system can be directed to target proteins with cancer-driving mutations in tumors, marking a significant advance in immunotherapy.

Brain Cancer Featured Neurology Neuroscience

·November 4, 2024·4 min read

Omega-3 and 6 Linked to Lower Cancer Risk

Higher levels of omega-3 and omega-6 fatty acids are linked with a lower risk of several types of cancer, including brain, colon, stomach, and lung cancer, according to a study of over 250,000 participants. The findings highlight the potential of these "healthy fats" in cancer prevention, regardless of BMI or lifestyle. The study also suggests that omega-6 benefits are particularly effective for younger adults, especially women. Results open the door to dietary adjustments that may aid in reducing cancer risk.

Brain Cancer Featured Neurology Neuroscience

·November 4, 2024·5 min read

New Cell Targets Offer Hope for Treating Glioblastoma

Researchers have identified potential drug targets in glioblastoma cancer stem cells, providing a new approach to treat this aggressive brain cancer. By analyzing stem cells derived from patient tumors, scientists found two primary cell subtypes responsible for tumor growth, each with unique vulnerabilities.

Brain Cancer Featured Neuroscience

·October 22, 2024·4 min read

Exercise During Chemotherapy Boosts Cognitive Function

A recent clinical trial found that women who began an aerobic exercise program during chemotherapy for breast cancer reported improved cognitive function and quality of life compared to those who received standard care. Participants in the exercise group felt they could better concentrate and remember things, helping to reduce the effects of "chemo-brain."

Brain Cancer Featured Neuroscience

·October 11, 2024·4 min read

Ferroptosis Findings Offer Hope for Cancer and Cell Protection

Scientists have uncovered a new pathway regulating cell death, or ferroptosis, which could pave the way for innovative cancer treatments. By examining how oxidative stress damages lipid membranes, the team found that the proteasome recycling system becomes clogged, accelerating cell destruction.

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Cancer

Glioblastoma Syncs With the Body’s Internal Clock

Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

Ketogenic Diet Enhances CAR-T Cancer Therapy

Targeted Immune Cells Destroy Brain Tumors

AI Improves Brain Tumor Detection

Cannabis Use Linked to Epigenetic Changes, Cancer Risk

CAR T-Cell Therapy Recruits Brain’s Defenses Against Glioblastoma

Novel Vaccine Targets Deadly Brain Tumors with Precision

Omega-3 and 6 Linked to Lower Cancer Risk

New Cell Targets Offer Hope for Treating Glioblastoma

Exercise During Chemotherapy Boosts Cognitive Function

Ferroptosis Findings Offer Hope for Cancer and Cell Protection

Teenage Cannabis Use Linked to 52% Higher Schizophrenia Risk

Physical Activity Rewires the Traumatized Brain

Gene Linking Schizophrenia to Decision-Making Found

Positive Childhood Experiences and Special Health Care Needs

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