Brain CancerFeaturedGeneticsNeurologyNeuroscience·April 14, 2025·4 min readShared Protein Link Found Between Parkinson’s and CancerA new study reveals that the protein alpha-synuclein, known for its role in Parkinson’s disease, also contributes to the development of melanoma by promoting excessive DNA repair and cell proliferation. While in neurons, excess alpha-synuclein leads to cell death, in melanoma cells it enables uncontrolled growth by recruiting repair proteins to DNA breaks.Read More
Brain CancerFeaturedNeurologyNeuroscience·April 10, 2025·8 min readBrain Circuit Discovery Links Cancer Fatigue to InflammationNew research shows that apathy and fatigue in advanced cancer are driven not by physical decline, but by inflammation-sensing neurons that suppress motivation. Scientists discovered that inflammation triggers a brainstem-to-reward-center pathway that reduces dopamine, the brain’s key motivation chemical.Read More
Brain CancerFeaturedNeurologyNeuroscience·April 9, 2025·3 min readChemotherapy Disrupts Brain ConnectivityNew research reveals that chemotherapy can lead to rapid and widespread changes in brain connectivity in breast cancer patients. Using functional MRI scans, scientists observed disruptions in the frontal-limbic system and cerebellar cortex, regions involved in executive function and memory.Read More
FeaturedGeneticsNeuroscience·January 10, 2025·3 min readHow Fiber Fuels Anti-Cancer Gene ActivityFiber digestion produces short-chain fatty acids like propionate and butyrate, which directly alter gene expression with anti-cancer effects, according to new research. The study found that these fatty acids influence genes involved in cell proliferation, differentiation, and apoptosis, key processes that control tumor growth. Researchers demonstrated these epigenetic changes in human cells and mouse models, highlighting fiber's systemic impact on health.Read More
AutismBrain CancerFeaturedGeneticsNeuroscience·January 9, 2025·8 min readYouthful Brain Stem Cells Linked to Autism and Brain CancerResearchers have identified a unique stem cell in the young brain capable of maturing into multiple cell types, potentially explaining the origins of autism and glioblastoma. These stem cells show gene expression patterns that regulate early brain development and, when disrupted, could lead to neurological conditions.Read More
Brain CancerFeaturedGeneticsNeuroscience·January 8, 2025·7 min readAI Reveals Gene Activity in Human CellsResearchers have developed an AI model that accurately predicts gene activity in any human cell, providing insights into cellular functions and disease mechanisms. Trained on data from over 1.3 million cells, the model can predict gene expression in unseen cell types with high accuracy. It has already uncovered mechanisms driving a pediatric leukemia and may help explore the genome's "dark matter," where most cancer mutations occur.Read More
Brain CancerFeaturedNeuroscience·December 31, 2024·6 min readRevolutionizing Brain Diagnostics with Light and AIA new "molecular lantern" technique allows researchers to monitor molecular changes in the brain non-invasively using a thin light-emitting probe. This innovative tool utilizes Raman spectroscopy to detect chemical changes caused by tumors, injuries, or other pathologies without altering the brain beforehand.Read More
Brain CancerFeaturedNeurologyNeuroscience·December 12, 2024·8 min readGlioblastoma Syncs With the Body’s Internal ClockGlioblastoma, an aggressive brain cancer, syncs its internal clock to the host’s circadian rhythms, leveraging daily hormone cycles for growth. Blocking these signals slowed tumor progression in mice and revealed that the timing of treatments like dexamethasone (DEX) critically influences outcomes.Read More
Brain CancerFeaturedNeurologyNeuroscience·December 9, 2024·6 min readLab-Grown Tumor Models Mirror Glioblastoma Treatment ResponseGlioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.Read More
Brain CancerFeaturedNeuroscience·December 7, 2024·5 min readKetogenic Diet Enhances CAR-T Cancer TherapyResearchers have found that a ketogenic diet boosts CAR T cell therapy effectiveness by enhancing tumor control and survival in mice with lymphoma. The key is beta-hydroxybutyrate (BHB), a metabolite produced during ketosis, which CAR T cells prefer as an energy source over glucose. Laboratory models showed that BHB supplementation led to complete cancer remission in most mice and enhanced CAR T cell expansion.Read More
Brain CancerFeaturedNeurologyNeuroscience·December 6, 2024·7 min readTargeted Immune Cells Destroy Brain TumorsResearchers have created a "molecular GPS" to guide immune cells directly to the brain, enabling precise targeting of tumors like glioblastoma. These cells use a unique protein code to navigate and attack cancer while sparing healthy tissue, offering a safer alternative to traditional treatments. In mice, this technology successfully cleared tumors, prevented recurrences, and reduced brain inflammation in models of multiple sclerosis.Read More
Brain CancerFeaturedNeurologyNeuroscience·November 20, 2024·6 min readAI Improves Brain Tumor DetectionAI models trained on MRI data can now distinguish brain tumors from healthy tissue with high accuracy, nearing human performance. Using convolutional neural networks and transfer learning from tasks like camouflage detection, researchers improved the models’ ability to recognize tumors.Read More
