Inadequate sleep can harm brain organization in early adolescence, researchers report. The disorganization can have an impact on cognitive processes, including attention, memory, emotional regulation, and controlling behaviors.
RAGE-Control, a video game system that utilizes biofeedback to regulate heart rate, reduces stress, oppositional behavior, and aggression by training children to stay calm during stressful and frustrating situations.
A new bio-inspired slow-release system for site 1 sodium channel blockers helps release anesthesia, providing prolonged nerve blocking with minimal toxicity.
Alpha-2-adrenergic agonists appear to be effective at reducing symptoms associated with ADHD in preschool-aged children, and have fewer side effects than traditional stimulants used to treat ADHD.
Physical exercise was associated with more efficiently organized, robust, and flexible networks in the preteen brain.
A study of patients with polymicrogyria sheds new light on the role the ATP1A3 gene plays in early brain development.
Children who embark on regular exercise have marked differences in brain structure, flexibility, organization, and have more robust neural networks than those who exercise less frequently.
Mouse study reveals the choroid plexus can act as a conduit for inflammation that can arise from maternal inflammation, impacting fetal brain development.
Prosopagnosia, or "face-blindness", involves an entire network, not just one area of the brain. The findings may shed light on poor facial processing abilities associated with autism.
TH17 cells produced increased amounts of SerpinB1, a protein implicated in multiple sclerosis symptoms. SerpinB1 cells were identified with antibodies targeting the CXCR6 surface protein. Using monoclonal antibodies to target CXCR6, the cells disappeared significantly, and the mice primed to develop MS did not develop the disease.
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A machine learning algorithm can accurately detect abnormalities in pupil dilation, which are predictive of ASD, in mouse models. The AI can also detect if a female has Rett syndrome with 80% accuracy. The system could be used to detect autism in infants and toddlers.
Researchers report children who experience deprivation early in life have impaired memory and executive function between the ages of 8 and 16 compared to peers who were placed in quality foster homes.