Using gene editing to boost the production of SOD3 in the choroid plexus reduced oxidative damage to brain tissue and cerebral spinal fluid in mice exposed to methotrexate.
Findings implicate copy number variants (CNVs) in the development of childhood psychosis. Researchers recommend chromosomal array testing for children with psychosis.
Smaller brain volume found in fetal MRI brain scans predicts the outcome of children with congenital heart disease across all domains of neurodevelopment.
An abundance of newly acquired mutations in the mutations that occur at an accelerated speed is a telling pattern of Alzheimer's disease, researchers report.
Inadequate sleep can harm brain organization in early adolescence, researchers report. The disorganization can have an impact on cognitive processes, including attention, memory, emotional regulation, and controlling behaviors.
RAGE-Control, a video game system that utilizes biofeedback to regulate heart rate, reduces stress, oppositional behavior, and aggression by training children to stay calm during stressful and frustrating situations.
A new bio-inspired slow-release system for site 1 sodium channel blockers helps release anesthesia, providing prolonged nerve blocking with minimal toxicity.
Alpha-2-adrenergic agonists appear to be effective at reducing symptoms associated with ADHD in preschool-aged children, and have fewer side effects than traditional stimulants used to treat ADHD.
Physical exercise was associated with more efficiently organized, robust, and flexible networks in the preteen brain.
A study of patients with polymicrogyria sheds new light on the role the ATP1A3 gene plays in early brain development.
Children who embark on regular exercise have marked differences in brain structure, flexibility, organization, and have more robust neural networks than those who exercise less frequently.
Mouse study reveals the choroid plexus can act as a conduit for inflammation that can arise from maternal inflammation, impacting fetal brain development.
