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          blood-brain barrier

          This shows DNA.
          FeaturedGeneticsNeurologyNeuroscience
          ·June 28, 2024·4 min read

          New Molecular Signatures Found for Alzheimer’s Disease

          Researchers identified unique molecular signatures of blood-brain barrier dysfunction in Alzheimer's disease. They discovered altered communication between brain vascular cells mediated by VEGFA and SMAD3 molecules. These findings could lead to new diagnostic biomarkers and treatment options for Alzheimer's.
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          This shows a brain.
          FeaturedNeuroscience
          ·June 3, 2024·4 min read

          Could Your Brain Have Its Own Microbiome?

          Recent research suggests the brain might host its own microbiome, challenging the long-held belief that it is a sterile organ. Studies have found bacterial and fungal genetic material in brain tissues, particularly in those with Alzheimer’s. The brain microbiome could be linked to diseases, offering potential new treatment avenues. However, much remains unknown about how microbes enter and affect the brain.
          Read More
          This shows a virus and neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·May 16, 2024·7 min read

          Engineered Virus Crosses Blood-Brain Barrier to Deliver Gene Therapy

          Researchers have engineered a gene therapy delivery vehicle that efficiently crosses the blood-brain barrier in mice. This breakthrough uses a human protein to ferry therapeutic genes into the brain, potentially paving the way for safer and more effective treatments for various brain diseases, including neurodevelopmental and neurodegenerative disorders.
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          This shows a brain.
          Brain CancerFeaturedNeurologyNeuroscience
          ·May 6, 2024·6 min read

          Nanoparticles Penetrate Blood-Brain Barrier to Treat Cancer

          Researchers developed a novel nanoparticle that can cross the blood-brain barrier to target both primary breast tumors and brain metastases simultaneously. This dual-action approach utilizes a biodegradable polymer loaded with two prodrugs targeting cancer cell mitochondria.
          Read More
          This shows blood vessels.
          FeaturedNeuroscience
          ·April 3, 2024·3 min read

          How Brain Blood Vessels Develop

          Blood vessels in the brain develop under unique rules, challenging longstanding beliefs about vascular formation. This research identified a specific enzyme crucial for the invasion of blood vessels into the brain, linking the formation of these vessels directly with the establishment of the blood-brain barrier.
          Read More
          This shows a brain.
          FeaturedNeuroscience
          ·September 26, 2023·3 min read

          Probing E-Cig and Alcohol’s Joint Assault on the Blood-Brain Barrier

          E-cigarettes, popular among teens, have been linked to increased alcohol and drug consumption. Now, with NIH funding, researchers seeks to understand the effects of combining e-cigarettes and alcohol on our brain's protective layer: the blood brain barrier.
          Read More
          This shows a brain.
          FeaturedNeuroscience
          ·September 7, 2023·5 min read

          Is the Blood-Brain Barrier a Key to Behavior?

          The blood-brain barrier (BBB) in carpenter ants isn't just a protective boundary, but actively shapes ant behavior. The BBB produces an enzyme called Juvenile hormone esterase (Jhe) that degrades the Juvenile Hormone (JH3), which promotes foraging behavior.
          Read More
          This shows a woman's head.
          FeaturedGeneticsNeuroscience
          ·July 12, 2023·7 min read

          Unlocking the Secrets of the Blood-Brain Barrier

          New research reveals crucial insights about the blood-brain barrier's permeability. Using zebrafish and mice models, researchers identified a neuron-originating signal pivotal for the barrier's formation and maintenance.
          Read More
          This shows a brain
          FeaturedNeuroscience
          ·April 21, 2023·3 min read

          Tiny Polystyrene Particles Detected in the Brain Just Two Hours After Ingestion

          Two hours after ingestion, tiny particles of polystyrene, a widely used plastic commonly used for food packing, can be detected in the brain. These plastic particles can increase the risk of neuroinflammation and neurodegeneration.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·March 9, 2023·4 min read

          Transporting Antibodies Across the Blood–Brain Barrier to Treat Alzheimer’s Disease

          Researchers have developed a new method that uses antibody fragments encapsulated in nanomicelles which can cross the blood-brain barrier and reduce levels of amyloid-beta in the brains of mouse models of Alzheimer's disease.
          Read More
          This shows the outline of a head
          FeaturedNeurologyNeuroscience
          ·February 27, 2023·3 min read

          Researchers Detail Changes in the Blood-Brain Barrier Related to Alzheimer’s Disease

          In those with Alzheimer's disease, the choroid plexus becomes enlarged and has increased accumulation of abnormal inflammatory signatures.
          Read More
          This shows a blood vessel and neurons
          FeaturedNeuroscience
          ·February 17, 2023·6 min read

          Achieving a Better Understanding of How the Blood-Brain Barrier Works

          Researchers have created a new model of the blood-brain barrier that can mimic fluid flow to and from the brain.
          Read More
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          This shows a person in an interrogation room late at night. Brains are behind him.

          Exhaustion Loophole: How Sleep Deprivation Compromises Justice

          This shows a digital head and a person using a tablet in a dark room.

          Why Millions Are Turning to ChatGPT for Mental Health

          This shows a brain and sickle cells.

          How the Brain Compensates for Sickle Cell Disease

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          Why Learning Makes Brain Cells Work Together, Not Apart

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