The signals that originate in the cells of the blood-brain barrier also play a direct role in controlling what happens to the neurons the barrier is protecting.
Researchers have developed drug-carrying nanoparticles that cross the blood-brain barrier, allowing for more effective delivery to the brain than conventional medications. The nanoparticles can get into tumors and kill glioblastoma brain cancer cells.
New findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.
Lipids entering the brain as a result of damage to the blood-brain barrier may be a determining cause of Alzheimer's disease. Researchers say simple lifestyle changes could reduce Alzheimer's risks by reducing the impact on the BBB and decrease Alzheimer's associated brain damage.
Researchers have created a comprehensive atlas of cell types in the brain's cerebrovascular system.
Applying rapid short pulses of ultrasound can non-invasively deliver liposomes directly to the brain, across the blood-brain barrier.
A newly developed technique allows researchers to consistently and reproducibly open the blood-brain barrier in animal models.
In fruit flies, there is a second barrier in the brain where glial cells ensure a spatial separation for different functional compartments.
Silver and zinc oxide nanomaterials are able to pass through an in vitro blood-brain barrier model in the form of both particles and dissolved ions.
A new imaging study reveals how the MFSD2A transporter protein provides a gateway for omega-3 fatty acids to enter the brain.
A study in fruit fly models of autism reveals sleep disruption associated with the neurodevelopmental disorder is associated with elevated levels of serotonin. The origin of the higher levels of serotonin was discovered to be in glial cells in the blood-brain barrier.
DP-ASL, a new neuroimaging technique may help researchers identify early blood-brain barrier dysfunction associated with SVD.
