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bipolar depression

·January 28, 2022·4 min read

Patients With Schizophrenia, Major Depression and Bipolar Disorder Have Distinct Reward Neural Mechanisms

While patients with schizophrenia, major depressive disorder, and bipolar disorder experience a lack of motivation and anhedonia, the neural patterns of emotion-behavior dissociation differ between the disorders.

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·March 4, 2021·4 min read

Astrocytes Derived From Patients With Bipolar Disorder Malfunction

Astrocytes derived from pluripotent stem cells of bipolar patients provide suboptimal support for neural activity. The malfunction can be traced to the inflammation-promoting molecule, interleukin-6.

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Featured Neuroscience Open Neuroscience Articles Psychology

·June 11, 2019·3 min read

Brain activation provides individual-level prediction of bipolar disorder risk

Combining neuroimaging data with machine learning, researchers have identified patterns of brain activation during reward anticipation, associated with an increased risk of developing bipolar disorder. The patterns of neural activation predict the severity of mania symptoms in young adults who have not yet developed the disorder.

Featured Genetics Psychology

·January 20, 2019·5 min read

Specific Gene Variants May Increase Bipolar Risk

According to researchers, CPG2 is significantly less abundant in the brains of those with bipolar disorder. The findings could help develop new diagnostics and treatment for bipolar disorder.

Featured Neuroscience Psychology

·September 4, 2018·3 min read

Looking Inside the Brain to Distinguish Bipolar from Depression

A new neuroimaging study reveals those with bipolar depression have less activity in the amygdala and few connections with other areas of the brain than those with clinical depression.

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·August 9, 2018·4 min read

Evolutionary Changes in Brain May Have Led to Schizophrenia and Bipolar Disorder

According to researchers, neuropsychiatric disorders such as bipolar disorder and schizophrenia could be a byproduct of evolution.

Featured Open Neuroscience Articles Psychology

·June 12, 2018·7 min read

Poet Robert Burns May Have Suffered From Bipolar Disorder

Researchers examine the personal writings of Robert Burns, Scotland's national bard, and conclude he may have suffered from bipolar disorder.

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·June 11, 2018·3 min read

Mutation Links Bipolar Disorder to Mitochondrial Disease

Researchers report mitochondrial dysfunction may affect the activity of serotonergic neurons in mice with ANT1 mutations. The findings may provide insight into the origins of bipolar disorder.

Featured Neuroscience Psychology

·June 9, 2018·4 min read

How Depression Affects Your Thinking Skills

Typically, many people associate depression with feelings of sadness or despair. However, depression can also affect your cognitive abilities and memory. A new paper reviews the impact depression has on cognitive function and considers therapy options to help improve these often overlooked symptoms of the disorder.

Featured Genetics Psychology

·February 9, 2018·3 min read

Shedding Light on Genetic Overlap Between Major Psychiatric Disorders

Researchers have identified a range of psychiatric disorders, including schizophrenia and autism, that share physical characteristics at the molecular level. Specifically, the study identifies common patterns of neural gene expression. In addition, researchers note important differences in gene expression that distinguish the disorders.

Featured Genetics Open Neuroscience Articles Psychology

·February 5, 2018·5 min read

New Path For Bipolar Disorder Comes to Light

EGR3 and BDNF may play a critical role in the impaired cellular resilience seen in bipolar disorder, researchers report.

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·December 16, 2017·6 min read

After 12 Years of Searching for Cause of Bipolar Disorder, Researchers Conclude it Has Many

Following a 12 year long study, researchers have identified seven phenoclasses that can help doctors to diagnose and track the progression of bipolar disorder in patients.

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