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autophagy

Featured Neurology Neuroscience Open Neuroscience Articles

·April 18, 2019·4 min read

Blood pressure drug shows promise for treating Parkinson’s and dementia in animal study

Felodipine, a common hypertension medication, induces autophagy and clears aggregate-prone proteins associated with neurodegenerative diseases. The study reveals the drug clears mutant alpha-synuclein in the brains of mice at plasma concentrations to those seen in humans taking the medication. Felodipine appears to have some neuroprotective properties in mouse models of neurodegenerative diseases.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·April 10, 2019·4 min read

Protein pileup affects social behaviors through altered brain signaling

Study implicates disrupted autophagy and protein aggregation in the pathogenesis of autism schizophrenia and social behavior deficits in other disorders.

Featured Neurology Neuroscience Open Neuroscience Articles

·January 2, 2019·2 min read

Hyperactive Immune System Implicated in Aging Brain Disorders

According to a new study, the immune system may play a critical role in damage associated with neurodegenerative disorders such as Alzheimer's disease and ALS. The study reports altering Cdk5 results in the death of dopamine neurons and slowed autophagy.

Featured Genetics Neurology Open Neuroscience Articles

·March 7, 2018·3 min read

Strict Eating Schedule Can Lower Huntington’s Protein: Mouse Study

Restricting access to food within a strict time frame stimulates autophagy and lowers levels of the huntingtin protein in the brain, a new mouse study reveals.

Featured Neurology

·December 13, 2017·3 min read

Cellular Self Digestion Process Triggers Autoimmune Disease

A new study reveals how autophagy in certain immune cells can lead to the immune system attacking the central nervous system. The findings have implications for the treatment of autoimmune diseases, like multiple sclerosis.

Featured Neurology Open Neuroscience Articles

·November 22, 2017·4 min read

New Mechanism of Cell Death in Neurodegenerative Disorders

New finding could lead to novel therapeutic approaches in the treatment of neurodegenerative diseases.

Featured Neuroscience Open Neuroscience Articles

·November 2, 2017·3 min read

Synaptic Disorder

Targeting autophagy may help in the battle against ALS and other diseases that affect motor neurons, researchers report.

Featured Genetics Neuroscience

·September 16, 2017·7 min read

Unveiling the Mystery of Why We Age

Researchers have identified genes that contribute to autophagy. The findings shed light on the origins of the aging process and provide evidence that aging arises as a quirk of evolution.

Featured Neurology

·September 11, 2017·4 min read

Body’s Own Defense Against ALS Actually Drives Disease Progression at Later Stages

In early stages of ALS, autophagy helps to suppress disease progression, but accelerates the spread as the disease enters into later stages, researchers report.