Years of mouse research lead to discovery of how autophagy keeps neural stem cells ready to replace damaged brain and nerve cells.
Using transgenic mice, researchers find a lack of autophagy in neurons prevents the secretion of amyloid beta and the formation of β-amyloid plaques in the brain.
Researchers report an accumulation of glycogen in Lafora disease directly causes apoptosis, triggers autophagy and synaptic failure.
According to a new study, children with autism have an excess of synapses in the brain, due to a slowdown of the normal pruning process during development.
Researchers improve motor function and reduce brain shrinkage in animal models of HD by adjusting the levels of a signaling protein.
Researchers have identified a new gene associated with ALS.
A new study reveals how Schwann cells in the PNS degrade myelin following nerve injury.
Researchers have identified a transport defect in models of familial ALS which leads to the accumulation of damaged components.
According to a new study, when two debris clearing proteins don't work together as they should, Parkinson's disease can occur.
According to researchers, combining tricyclic antidepressants with blood thinners increased tumor autophagy in mouse models of glioblastoma brain cancer.
According to a new study, treatment with interferon-β gene therapy successfully prevents neuron death and disease effects in experimental models of neurodegenerative diseases.
According to a new study, a protein called Tet3FL removes methyl groups from specific genes, keeping them active.
