Blocking the breakdown of a specific fat molecule in the the brains of mice lead to reduced learning ability and memory retention. Additionally, researchers noted an increase of Alzheimer's related proteins. Findings may help explain how dementia may develop in humans, researchers say.
According to a new study, a protein called Tet3FL removes methyl groups from specific genes, keeping them active.
Loperamide, an anti-diarrhea medication, induces autophagy in glioblastoma brain cancer cells.
Researchers have identified the cellular and molecular mechanisms that regulate selective autophagy.
Years of mouse research lead to discovery of how autophagy keeps neural stem cells ready to replace damaged brain and nerve cells.
A new study reveals a gene that plays a key role in the formation of neural tube defects.
A new study reveals how Schwann cells in the PNS degrade myelin following nerve injury.
According to a new study, treatment with interferon-β gene therapy successfully prevents neuron death and disease effects in experimental models of neurodegenerative diseases.
Summary: A new study reports researchers have identified a substance that can help to induce the reversal of aging. Source:...
Felodipine, a common hypertension medication, induces autophagy and clears aggregate-prone proteins associated with neurodegenerative diseases. The study reveals the drug clears mutant alpha-synuclein in the brains of mice at plasma concentrations to those seen in humans taking the medication. Felodipine appears to have some neuroprotective properties in mouse models of neurodegenerative diseases.
Researchers improve motor function and reduce brain shrinkage in animal models of HD by adjusting the levels of a signaling protein.
A new mouse study reveals a breakdown in the process that clears brain cells of waste products precedes the buildup of amyloid plaques associated with Alzheimer's disease.