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Featured Neuroscience Open Neuroscience Articles

·May 19, 2017·5 min read

Disrupted Fat Breakdown in the Brain of Mice Makes Them Dumb

Blocking the breakdown of a specific fat molecule in the the brains of mice lead to reduced learning ability and memory retention. Additionally, researchers noted an increase of Alzheimer's related proteins. Findings may help explain how dementia may develop in humans, researchers say.

Featured Genetics Open Neuroscience Articles

·January 26, 2016·3 min read

Potential ‘Guardian’ Against Neurodegeneration Identified

According to a new study, a protein called Tet3FL removes methyl groups from specific genes, keeping them active.

Brain Cancer Featured Neurology Neuroscience

·December 23, 2020·4 min read

Anti-Diarrhea Drug Drives Cancer Cells to Cell Death

Loperamide, an anti-diarrhea medication, induces autophagy in glioblastoma brain cancer cells.

Featured Genetics Neuroscience Open Neuroscience Articles

·June 5, 2022·3 min read

Studying Autophagy to Help Us Understand the Mechanisms of Aging-Related Diseases

Researchers have identified the cellular and molecular mechanisms that regulate selective autophagy.

20 brain scans are shown and described well in caption..

Featured Genetics Neuroscience

·April 11, 2013·5 min read

Spring Cleaning in Your Brain: Stem Cell Research Shows How Important Autophagy Is

Years of mouse research lead to discovery of how autophagy keeps neural stem cells ready to replace damaged brain and nerve cells.

Featured Neuroscience Open Neuroscience Articles

·May 5, 2017·5 min read

Gene That Controls Birth Defect Common in Diabetes Identified

A new study reveals a gene that plays a key role in the formation of neural tube defects.

This image shows the proposed role of myelinophagy in a Schwann cell after nerve injury and axon degeneration.

Featured Neuroscience

·July 6, 2015·4 min read

Schwann Cells Clear Damaged Myelin and Guide Regeneration Following Nerve Damage

A new study reveals how Schwann cells in the PNS degrade myelin following nerve injury.

Diagram of a healthy neuron and one from a Parkinson's patient.

Featured Genetics Open Neuroscience Articles

·October 9, 2015·3 min read

Immune Gene May Prevent Alzheimer’s and Parkinson’s Disease

According to a new study, treatment with interferon-β gene therapy successfully prevents neuron death and disease effects in experimental models of neurodegenerative diseases.

Featured Genetics

·April 3, 2017·3 min read

Reversal of Aging Now Possible

Summary: A new study reports researchers have identified a substance that can help to induce the reversal of aging. Source:...

Featured Neurology Neuroscience Open Neuroscience Articles

·April 18, 2019·4 min read

Blood pressure drug shows promise for treating Parkinson’s and dementia in animal study

Felodipine, a common hypertension medication, induces autophagy and clears aggregate-prone proteins associated with neurodegenerative diseases. The study reveals the drug clears mutant alpha-synuclein in the brains of mice at plasma concentrations to those seen in humans taking the medication. Felodipine appears to have some neuroprotective properties in mouse models of neurodegenerative diseases.

The image shows a single striatal neuron (yellow) transfected with nuclear inclusion (orange) mHtt, other neurons in background (blue).

Featured Genetics Neurology

·January 5, 2015·4 min read

Animal Study Points to a Treatment for Huntington’s Disease

Researchers improve motor function and reduce brain shrinkage in animal models of HD by adjusting the levels of a signaling protein.

Featured Neurology Neuroscience

·June 2, 2022·5 min read

Evidence Mounts for Alternate Origins of Alzheimer’s Disease Plaques

A new mouse study reveals a breakdown in the process that clears brain cells of waste products precedes the buildup of amyloid plaques associated with Alzheimer's disease.

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