Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect.
Combining neuroimaging data with machine learning, researchers report musical pleasure depends on a dynamic interplay between prospective and retrospective states of expectation.
When a person listens to another person talking, their brain waves alter to select specific features of the speaker's voice and tune out other voices.
People with schizophrenia who experience auditory hallucinations have greater activation in specific areas of the auditory cortex in response to sound frequencies. The mapping of sound frequency in the auditory cortex is scrambled in those with schizophrenia, suggesting a disruption in the normal processes for organized sound representation in the brain. As the tonotopic map is established during infancy and remains stable throughout life, the findings suggest vulnerability for auditory hallucinations is linked to defects in the organization of the auditory system during infantile development. This precedes speech development and the onset of psychiatric symptoms.
Nonverbal children on the autism spectrum have a slower response to auditory stimulation. The longer response times were associated with poor communication skills. Brain imaging of the auditory cortex could serve as a biomarker for measuring the likelihood of language impairment in those with ASD.
Rodent study reveals noise-induced hearing loss is associated with elevated expression of proinflammatory cytokines and microglia activation in the primary auditory cortex. Pharmacologically depleting microglia helps prevent tinnitus in mice with noise-induced hearing loss.
Study of macaque monkeys reveals speech and music may have shaped the human brain's auditory networks. Researchers found specific areas of the human brain have a stronger preference for pitch than that of primates, raising the possibility certain sounds, which are embedded in music and speech, may have shaped the organization of our brains.