Anhedonia and depression arise when POMC neurons in the arcuate nucleus of the hypothalamus become hyperactive as a result of chronic stress. Reducing the activity also reduces feelings of depression and loss of pleasure.
Induced changes in the function of AgRP neurons may contribute to depression, researchers report.
The protein ACBP directly influences neurons that help both rodents and humans maintain a healthy weight.
Researchers report on the role the arcuate nucleus plays in metabolic regulation and appetite suppression following exercise.
Researchers are testing a new drug, which can be used as an alternative to estrogen therapy for menopausal women. Early data shows the drug significantly reduced the total number of weekly hot flashes in women by 73% and was well tolerated by those who took it.
A new study could have positive implications for developing anti obesity treatments.