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antipsychotics

·December 6, 2024·5 min read

Antipsychotics Worsen Behavior in Dementia

A study of 500,000 Canadian nursing home residents found antipsychotic medications significantly worsened behaviors in patients, with nearly 68% experiencing increased issues. Antipsychotics are often prescribed "off-label" for dementia-related symptoms, despite serious side effects like tremors and cognitive decline. Researchers advocate for person-centered care, emphasizing non-drug therapies like music, art, and exercise to address behavioral issues.

Featured Neuroscience Psychology

·July 18, 2023·4 min read

Study Challenges Longstanding Beliefs About Action of Antipsychotic Medications

Researchers uncovered a pivotal detail that could revolutionize schizophrenia treatment. Contrary to longstanding belief, antipsychotic drugs that mitigate overactive dopamine, a hallmark of schizophrenia, interact primarily with a different type of neuron than originally assumed.

Featured Neuroscience Psychology

·January 15, 2023·5 min read

Old Antipsychotic Drugs May Offer New Option to Treat Type 2 Diabetes

Diphenylbutylpiperidines (DPBPs), an older class of antipsychotic medications can effectively be repurposed to help treat type 2 diabetes, a new study reports.

Brain Cancer Featured Neuroscience Psychology

·September 6, 2022·4 min read

Antipsychotic Use Associated With Elevated Risk of Breast Cancer

Study reveals a moderate link between antipsychotic use and an increased risk of developing breast cancer.

Featured Neuroscience Psychology

·April 15, 2022·2 min read

Managing Excessive Weight Gain in Patients Being Treated With Antipsychotics

Researchers say 80% of people taking antipsychotics to manage schizophrenia or bipolar disorder experience considerable weight gain. Some patients report up to 33kg of weight gain following taking antipsychotic medications. A new study aims to explore ways of managing weight gain for patients taking antipsychotics.

Featured Genetics Neuroscience Psychology

·May 19, 2021·5 min read

Flies With Schizophrenia-Associated Genes Respond Well to Anti-Psychotics

Flies without the Rim gene or cac Cav2 channel function displayed numerous cognitive and behavioral deficits associated with schizophrenia, and had reductions in synaptic growth and neural calcium transients. Exposing the flies with Rim deficits to the common antipsychotic haloperidol reduced some of the schizophrenia-related behavioral symptoms.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 12, 2021·4 min read

Brain Immune System Linked to Psychosis

A link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of kynurenic acid in the brain.

Featured Neuroscience Psychology

·February 1, 2021·4 min read

Antipsychotic Prescriptions Rising Much Faster Than Psychosis Rates

While England has only seen a moderate rise in people being diagnosed with psychosis in recent years, prescription rates for antipsychotic medications have doubled.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·January 30, 2021·4 min read

Why Do Psychiatric Drugs Help Some, but Not Others?

Study reveals the function of a specific protein works differently in the brains of men and women. The findings help explain why some psychiatric disorders and resistance to treatments vary between the sexes.

Featured Open Neuroscience Articles Psychology

·September 30, 2020·4 min read

Antipsychotics for Treating Adult Depression Linked With Higher Mortality

Study reveals a link between people with depression who are prescribed newer antipsychotic medications and higher mortality risk.

Featured Neuroscience Psychology

·June 14, 2020·2 min read

Clozapine may cause obsessions and compulsions

The antipsychotic medication clozapine can trigger severe obsessive-compulsive symptoms (OCS) in patients. Adding aripiprazole can help manage clozapine-associated OCS.