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antipsychotics

·January 29, 2020·4 min read

How CBD takes effect in the brains of people with psychosis

During memory tasks, people with psychosis have different patterns of activity in the prefrontal and mediotemporal brain areas compared to those without the disorder. When exposed to cannabidiol (CBD), the activity of the brain areas became more like those seen in the controls for people with psychosis. Patients reported a decrease in symptoms of psychosis following one dose of CBD. Researchers stress that no definitive conclusions could be made about the effectiveness of CBD use over a sustained period.

Featured Genetics Neuroscience Psychology

·May 19, 2021·5 min read

Flies With Schizophrenia-Associated Genes Respond Well to Anti-Psychotics

Flies without the Rim gene or cac Cav2 channel function displayed numerous cognitive and behavioral deficits associated with schizophrenia, and had reductions in synaptic growth and neural calcium transients. Exposing the flies with Rim deficits to the common antipsychotic haloperidol reduced some of the schizophrenia-related behavioral symptoms.

Featured Neuroscience Psychology

·June 14, 2020·2 min read

Clozapine may cause obsessions and compulsions

The antipsychotic medication clozapine can trigger severe obsessive-compulsive symptoms (OCS) in patients. Adding aripiprazole can help manage clozapine-associated OCS.

Featured Psychology

·February 20, 2019·5 min read

Some Drug Combinations More Effective Than Others For Patients with Schizophrenia

A new study reveals some drug combinations may be more beneficial for those with schizophrenia. Researchers found people with schizophrenia who took antidepressants, in combination with other medications, were less likely to be hospitalized for mental health issues than those who started another antipsychotic.

This image shows a microscopic view of the frontal cortex of a mouse.

Featured Psychology

·March 9, 2015·6 min read

Newly Discovered Brain Pathway Could Solve Antipsychotic Mystery

Researchers provide possible new insights into psychiatric disorders such as schizophrenia.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 12, 2021·4 min read

Brain Immune System Linked to Psychosis

A link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of kynurenic acid in the brain.

Featured Neuroscience Psychology

·January 15, 2023·5 min read

Old Antipsychotic Drugs May Offer New Option to Treat Type 2 Diabetes

Diphenylbutylpiperidines (DPBPs), an older class of antipsychotic medications can effectively be repurposed to help treat type 2 diabetes, a new study reports.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 10, 2020·5 min read

Long-term medication for schizophrenia is safe

Long-term antipsychotic use does not increase the risk of physical morbidity leading to hospitalization.

Featured Open Neuroscience Articles Psychology

·September 30, 2020·4 min read

Antipsychotics for Treating Adult Depression Linked With Higher Mortality

Study reveals a link between people with depression who are prescribed newer antipsychotic medications and higher mortality risk.

Image shows the location of the striatum in the brain.

Featured Neuroscience Open Neuroscience Articles Psychology

·July 6, 2016·3 min read

Dopamine Receptor Blockage Could Be Cause For Side Effects of Some Antipsychotics

Researchers report a blockade of D2 receptors in interneurons can increase acetylcholine signaling above threshold on neighboring neurons, resulting in motor abnormalities.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·January 30, 2021·4 min read

Why Do Psychiatric Drugs Help Some, but Not Others?

Study reveals the function of a specific protein works differently in the brains of men and women. The findings help explain why some psychiatric disorders and resistance to treatments vary between the sexes.