Mouse study reveals the antibiotic azlocillin completely kills off the Borrelia burgdorferi bacteria at the onset of Lyme disease. Findings also suggest the drug could be effective for treating patients infected with drug-tolerant bacteria that may cause lingering symptoms.
Cannabigerol (CBG), a non-psychoactive cannabis compound, has antibiotic potential. Treating mice with MRSA, CBG worked as well as vancomycin, a powerful antibiotic, for treating the infection.
Ethnobotanical plant extracts, including Ghanaian quinine and Japanese knotweed, show strong activity against B.burgdorferi, outperforming current antibiotics for the treatment of Lyme disease.
A new deep learning algorithm helped researchers identify a powerful new antibiotic compound that kills many of the world's most problematic, disease-causing bacterias, including those which have so far been resistant to common antibiotics.
Mothers who were prescribed macrolide antibiotics, including erythromycin and azithromycin, early in pregnancy had an increased risk of their child being born with malformations, specifically cardiovascular malformations. However, researchers found no link between exposure to these antibiotics and an increased risk of neurodevelopmental disorders.
Gentamicin and G418, two aminoglycoside antibiotics, were effective at correcting genetic mutations associated with a specific form of frontotemporal dementia. The findings are promising for the treatment of frontotemporal dementia.
Excessive exposure to certain antibiotics can predispose a person to Parkinson's disease, with a delay of onset of up to 15 years.
Epigallocatechin (EGCG), a natural antioxidant found in green tea, may help in the fight against antibiotic-resistant bacteria. EGCG restores the activity of aztreonam, an antibiotic commonly used to treat infections caused by P. aeruginosa. The bacteria is resistant to major classes of antibiotics and is currently treated with a combination of drugs.
Cannabidiol (CBD), a non-psychoactive compound extract of marijuana, has the potential to be used as an antibiotic. Researchers found CBD was remarkably effective at killing a wide range of Gram-positive bacteria, including bacteria that are resistant to common antibiotics. Additionally, CBD does not lose its effectiveness after extended treatment.
A synthetic version of a fibupeptide, which is naturally produced by the microbiome, may help in the fight against antibiotic-resistant bacteria. Lugdunin has been shown to be effective against MRSA. The findings could help in the creation of a new class of antibiotics to treat infections currently resistant to drugs on the market.
FIASMA antidepressants, such as amitriptyline and desipramine, halt the growth of four different kinds of bacterial pathogens in cell cultures and animal models. The antidepressants have shown to be effective in killing intracellular bacteria in two chlamydia infections, as well as human granulocytic anaplasmosis, a tick-borne disease that attacks white blood cells.
Gastrointestinal and immune disorders, along with sleep disruptions and seizures often co-occur at similar points of time in those diagnosed under the autism spectrum. Analyzing patterns in diagnosis of co-occurring medical conditions allowed for the identification of three subtypes of children with ASD. The findings could provide new insight into the mechanics of ASD.