Researchers have identified an autophagy pathway in hair cells in the ear that's linked to permanent hearing loss that occurs as a result of exposure to aminoglycosides antibiotics in some patients.
Early life exposure to antibiotics has a long-lasting effect on the enteric nervous system, microbiome, and gut function.
Recent antibiotic use impacts the way in which people pay attention to negative facial expressions. Findings shed light on how antibiotic use can increase the risks of depression.
Zebrafish study finds antibiotics can have detrimental effects on the descendants of those exposed to them, including weaker immune systems.
Study reveals a causal mechanism for pain reduction may be due to an antibiotic-induced shift in the gut's amino acid concentrations.
Early-life exposure to antibiotics could impact brain development in areas associated with emotional and cognitive function, a new study reports. Researchers found penicillin exposure in infant mice altered the microbiome and gene expression in key areas of the developing brain.
Researchers have identified an association between antibiotics administered to children aged two and under, and an increased risk of ongoing conditions ranging from ADHD to obesity. Children exposed to numerous courses of antibiotics as toddlers were more likely to be diagnosed with continuous conditions later in childhood. The study speculates that while antibiotics may only have a transient effect on the developing microbiome, this may have an impact on long-term illness.
Early-life exposure to antibiotics may impact brain signaling pathways associated with social behavior and pain regulation. Young mice treated with antibiotics had reduced expression of receptors that mediate endorphin, oxytocin, and vasopressin signaling in the frontal cortex.
Immunization with the vaccines for pneumococcal conjugate and rotavirus reduces the rates of acute respiratory infections and gastrointestinal infections in small children, thus reducing the need for antibiotic medications. Researchers say if universal childhood vaccination is achieved, an additional 40 million cases of antibiotic-treated illnesses could be prevented each year.
Mouse study reveals the antibiotic azlocillin completely kills off the Borrelia burgdorferi bacteria at the onset of Lyme disease. Findings also suggest the drug could be effective for treating patients infected with drug-tolerant bacteria that may cause lingering symptoms.
Ethnobotanical plant extracts, including Ghanaian quinine and Japanese knotweed, show strong activity against B.burgdorferi, outperforming current antibiotics for the treatment of Lyme disease.