An antibody called HAE-4 targets APOE and removes Alzheimer's related amyloid plaques in mouse models. The antibody improves blood vessel function in the brain without raising the risk of brain bleeds. Read More
Amyloid-beta38 may have protective benefits against Alzheimer's disease, researchers report. Read More
Major surgery can trigger different patterns of cognitive alterations depending on previous presence, or absence, of Alzheimer's pathologies. Read More
Impaired blood flow to specific areas of the brain coincides with Tau buildup in Alzheimer's patients. As cognition declines, the relationship between vascular dysfunction and Tau accumulation strengthens. Read More
Amyloid plaques form in the same location and spread in the same way in the brains of people with both obstructive sleep apnea and Alzheimer's disease. Read More
Current sleep patterns could help determine your risk of developing Alzheimer's disease as you age. People who experience more fragmented sleep and less non-REM slow-wave sleep are more likely to have increased levels of amyloid-beta. Read More
IFITM3, a protein that plays a role in the immune response to pathogens, also plays a key role in the accumulation of amyloid-beta plaques. As IFITM3 directly affects plaque formation, researchers suggest both viral and bacterial infections could increase the risk of Alzheimer's development. Read More
Early postmenopausal estrogen replacement therapy may protect some women from developing Alzheimer's disease. Read More
Study reveals a link between amyloid-beta accumulation in the brain and lower levels of insulin and insulin resistance. Read More
Analyzing nasal discharge could be a new tool in diagnosing and monitoring the progression of Alzheimer's disease. Researchers found certain Alzheimer's related proteins can be detected in nasal discharge. Read More
Salt crystals can precipitate at low concentrations due to local density fluctuations. Their repeated precipitation dissolution behavior promotes amyloid-beta peptide aggregation. Read More
Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias. Read More
