New Mechanism by Which Alzheimer’s Spreads Through the Brain
According to researchers, exosomes can transport toxic aggregates of amyloid beta to new neurons in the brain.... Read More...
amyloid-beta
How Does Alcohol Influence Alzheimer’s Development?
A new study reports alcohol may impede the clearance of amyloid beta, a protein associated with Alzheimer's disease, in the brain.... Read More...
Understanding the Origins of Alzheimer’s Disease
Researchers investigate the role the BMI1 gene plays in the onset and development of Alzheimer's disease. The study reports the loss of BMI1 triggers and increased production of amyloid beta and decreases neural ability to eliminate the protein.... Read More...
Vascular Risk Interacts with Amyloid Levels to Increase Age Related Cognitive Decline
Vascular risk factors appear to have a negative synergistic effect with amyloid beta levels in the brain, researchers report. The study suggests a combination of increased vascular risk and higher amyloid levels in the brain can predict more rapid cognitive decline during aging.... Read More...
Study Provides Robust Evidence of Sex Differences with Alzheimer’s Gene
According to researchers, Alzheimer's disease may be more prevalent in women, not simply because they live longer on average, but due to the APOE E4 gene. Researchers found the APOE association was greater for women in the Tau pathway than in men. However, there was no difference between APOE expression in the amyloid pathway in women compared to men.... Read More...
Brain Cholesterol Linked to Increased Alzheimer’s Risk
University of Cambridge researchers report cholesterol may play a role in the onset of Alzheimer's disease. Researchers discovered cholesterol can trigger amyloid beta to aggregate, which can lead to neuron death.... Read More...
New Model Could Uncover Important Answers in Alzheimer’s Research
Researchers have developed a new rat model of Alzheimer's disease that can be used to study the accumulation of amyloid plaques.... Read More...
Brain Activity Study Offers Potential Insight into Alzheimer’s Disease
A new study may provide key insights into the risk of developing Alzheimer's disease. Researchers report people with higher levels of amyloid beta showed less activity in brain areas associated with working memory when engaged in cognitively demanding tasks.... Read More...
Alzheimer’s Plaque Affects Different Brain Cells Differently
Alzheimer's linked protein, amyloid beta, appears to do very little harm to glial cells, at least in fruit flies, researchers report.... Read More...
Lack of Sleep May Be Linked to Risk Factor for Alzheimer’s
A new study reveals sleep deprivation can lead to an immediate increase in amyloid beta. ... Read More...
Overlapping Mechanisms in HIV Cognitive Disorders and Alzheimer’s
A new Journal of Neuroscience study reports elevated levels of BACE1, an enzyme associated with neuronal damage in Alzheimer's disease, were identified in postmortem brain samples of those with HIV.... Read More...
Researchers Fix Genetic Risk Factor of Alzheimer’s in Human Brain Cells
Researchers report they have successfully erased damage caused by Apoe4 in Alzheimer's patients by altering the gene into a harmless Apoe3-like version. ... Read More...