amyloid-beta

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amyloid-beta

·September 27, 2022·4 min read

New Model of Alzheimer’s as an Autoimmune Disease

Researchers propose a new model for Alzheimer's disease (AD2) that considers the neurodegenerative disease as an autoimmune disease that attacks the brain. Considering Alzheimer's as an autoimmune disorder could spark a new line of therapies to treat the disease.

Featured Neurology Neuroscience

·August 17, 2022·4 min read

How DDT Exposure Contributes to Alzheimer’s Disease Risk

DDT exposure causes sodium channels to remain open, leading to increased neural firing and an increased release of amyloid beta peptide. Blocking the channels with tetrodotoxin reduces the toxic amyloid protein by increasing the production of the amyloid precursor protein.

Featured Neurology Neuroscience

·August 11, 2022·6 min read

Researchers Explore the “Dark Side” of Alzheimer’s Disease Revealing New Biomarkers

A new collection of articles explores mapping brain overexcitability that underpins the dysregulation of vigilance, sleep-wake cycles, and validating effective biomarkers for Alzheimer's disease.

Featured Neurology Neuroscience

·August 1, 2022·6 min read

Is Everything We Think We Know About Alzheimer’s Wrong?

Recent scandals in Alzheimer's research and problems with medications designed to help those with Alzheimer's but failing to deliver sufficient results have researchers questioning the overwhelming focus on amyloid-beta in Alzheimer's research.

Featured Neurology Neuroscience

·July 31, 2022·3 min read

How a Neurotransmitter May Be the Key in Controlling Alzheimer’s Toxicity

Study reveals how somatostatin and copper affect amyloid beta in Alzheimer’s disease pathology.

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Featured Neurology Neuroscience

·July 15, 2022·4 min read

Whole Blood Exchange Could Offer Disease-Modifying Therapy for Alzheimer’s Disease

Whole blood exchange effectively decreases the formation of amyloid beta in the brains of mouse models of Alzheimer's disease.

Featured Neurology Neuroscience

·June 22, 2022·5 min read

How the Astrocytic Urea Cycle in the Brain Controls Memory Impairment in Alzheimer’s Disease

Study reveals the role of the urea cycle in the brain and explores the dual nature of astrocytes in the brains of those with Alzheimer's pathology.

Featured Neurology Neuroscience

·June 20, 2022·2 min read

Blood Vessel Breakthrough Major Step Towards Alzheimer’s Treatment

A smaller version of the amyloid-beta protein, AB 1-40, builds up on the wall of small arteries and reduces blood flow to the brain, a new study reports.

Featured Neurology Neuroscience

·June 7, 2022·3 min read

Rapamycin Increases Alzheimer’s-Associated Plaques in Mice

Rapamycin, a drug approved for the treatment of cancer and transplant patients increases amyloid-beta protein plaques in the brains of mice.

This shows the cells and temperature gradiants

Featured Neurology Neuroscience

·June 5, 2022·5 min read

Alzheimer’s Disease Causes Cells to Overheat and ‘Fry Like Eggs’

The heat produced by amyloid-beta aggregation may cause other, healthy amyloid-beta to aggregate, causing more and more aggregates to form. However, with the addition of a novel drug compound, amyloid-beta aggregation can be stopped and the cell temperature lowered.

Featured Neurology Neuroscience

·June 2, 2022·5 min read

Evidence Mounts for Alternate Origins of Alzheimer’s Disease Plaques

A new mouse study reveals a breakdown in the process that clears brain cells of waste products precedes the buildup of amyloid plaques associated with Alzheimer's disease.

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Featured Neurology Neuroscience

·May 14, 2022·6 min read

Combination of ‘Feelings’ and Measurements Suggest Alzheimer’s in the Early Stage

A combination of patient-reported subjective cognitive impairment and measurable clinical symptoms, such as amyloid-beta accumulation in the cerebrospinal fluid, may help in the early diagnosis of Alzheimer's disease.

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