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Alzheimer’s disease

·January 23, 2024·5 min read

Brain Thinning Predicts Alzheimer’s 10 Years Before Symptoms

Researchers identified cortical gray matter thinning as a potential early biomarker for dementia. In a study involving 1,500 participants from diverse backgrounds, thinner cortical gray matter was linked to a higher risk of developing dementia 5 to 10 years before symptoms appeared.

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·January 23, 2024·4 min read

Strange Visual Symptoms Could Indicate Early Alzheimer’s

A study reveals new insights into posterior cortical atrophy (PCA), an early symptom of Alzheimer’s disease. Analyzing data from over 1,000 patients globally, they found that 94% of PCA cases predict Alzheimer's, with the rest linked to conditions like Lewy body disease.

Featured Genetics Neurology Neuroscience

·January 22, 2024·8 min read

Ancient DNA Reveals Secrets of High Modern Alzheimer’s and MS Rates

Researchers have created a vast gene bank from nearly 5,000 ancient humans, offering unprecedented insights into the historical spread of genes and diseases. This groundbreaking study linked the spread of multiple sclerosis (MS) genes to ancient migrations and discovered that genes increasing the risk of diseases like Alzheimer's originated from hunter-gatherers.

Featured Genetics Neurology Neuroscience

·January 18, 2024·5 min read

RNA Interference Plays Key Role in Alzheimer’s Disease

A new study suggests that RNA interference plays a crucial role in the disease. Researchers discovered that aging and Alzheimer’s-affected brains have an imbalance between toxic and protective short RNAs (sRNAs), leading to brain cell death and DNA damage.

Featured Neurology Neuroscience

·January 10, 2024·3 min read

Five Biological Variants of Alzheimer’s Discovered

Researchers have identified five biological variants of Alzheimer's disease through cerebrospinal fluid analysis, shedding new light on the complexity of the condition. These variants differ in amyloid production, blood-brain barrier integrity, nerve cell growth, protein synthesis, and immune system functioning.

Featured Genetics Neurology Neuroscience

·January 8, 2024·5 min read

Novel Gene Linked to Range of Neurodegenerative Diseases Identified

Researchers uncovered a crucial link between the gene Angiogenin (ANG) and age-related neurodegenerative diseases such as frontotemporal dementia (FTD), motor neuron disease (MND), and Parkinson's disease. In its mutated form, ANG causes stem cells to delay their differentiation into specialized nerve cells, leading to neurodevelopmental defects.

Featured Neurology Neuroscience

·December 26, 2023·6 min read

Uncovering the Hidden Risks of Young-Onset Dementia

A new study reveals 15 risk factors for young-onset dementia, challenging the notion that genetics are the sole cause. These factors, ranging from education and socioeconomic status to lifestyle and health issues, offer hope for prevention.

Featured Genetics Neurology Neuroscience

·December 15, 2023·5 min read

Alzheimer’s Alters COVID-19 Response in Olfactory Cells

Researchers uncovered how Alzheimer's Disease (AD) impacts COVID-19 outcomes through changes in the olfactory mucosal cells. Their study focused on individuals with AD who experienced exacerbated COVID-19 symptoms.

Featured Neurology Neuroscience

·December 14, 2023·5 min read

Stomach Bug Linked to Alzheimer’s Risk

A new study reveals a potential link between Helicobacter pylori infection and an increased risk of Alzheimer’s disease. Analyzing three decades of patient data, the researchers found that people over 50 with symptomatic H. pylori infection face an 11% higher risk of developing Alzheimer’s, which escalates to 24% a decade post-infection.

Featured Neurology Neuroscience

·December 12, 2023·7 min read

Novel Nanoparticle Delivery System Targets Alzheimer’s Inflammation

A new study demonstrates a breakthrough in Alzheimer's disease (AD) treatment using lipid nanoparticles (LNPs) to deliver small interfering RNA (siRNA) to the brain's microglia. This approach effectively suppresses a protein linked to Alzheimer's-related inflammation.

Featured Genetics Neurology Neuroscience

·December 12, 2023·6 min read

Rare Gene Mutation Shields Woman from Alzheimer’s

Researchers uncovered why a Colombian woman, despite carrying a genetic defect for Alzheimer’s, remained cognitively healthy into her 70s. The key lies in her possession of two copies of the rare Christchurch mutation in the APOE gene, which they replicated in a mouse study.

Featured Neurology Neuroscience

·December 7, 2023·6 min read

Serotonin Drop Linked to Memory Decline in Early Alzheimer’s Progression

Researchers discovered a potential link between lower levels of serotonin, the "happiness" chemical, and mild cognitive impairment (MCI), which could advance our understanding of Alzheimer's Disease (AD). Their study indicates that individuals with MCI have significantly reduced serotonin transporter levels, a factor that might contribute to memory problems and potentially AD.