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          Alzheimer’s disease

          This shows a brain and a bottle of herbicide.
          FeaturedNeurologyNeuroscience
          ·December 4, 2024·9 min read

          Herbicide Exposure Linked to Long-Term Brain Inflammation, Alzheimer’s

          New research reveals that glyphosate, a widely used herbicide, can cause lasting brain inflammation and accelerate Alzheimer’s-like pathology in mice. Even short-term exposure resulted in persistent inflammatory markers and neurological damage, including anxiety-like behaviors and premature death. The study found that glyphosate’s metabolite, aminomethylphosphonic acid, accumulates in brain tissue, raising concerns about its long-term safety for humans.
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          This shows an older man running.
          FeaturedNeurologyNeuroscience
          ·December 4, 2024·3 min read

          Study Links Muscle Loss to Alzheimer’s Risk

          New research shows that skeletal muscle loss, measured through temporalis muscle size on brain MRIs, is associated with a higher risk of developing Alzheimer’s disease. A study of 621 older adults found that those with smaller temporalis muscles were 60% more likely to develop dementia and experienced greater cognitive and brain volume decline over nearly six years.
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          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·December 2, 2024·5 min read

          Visceral Fat May Indicate Alzheimer’s Risk Decades Before Symptoms

          A new study links visceral fat, a deep layer of abdominal fat, to increased brain amyloid and tau proteins—key markers of Alzheimer’s disease—decades before dementia symptoms arise. Researchers found that visceral fat accounted for 77% of the relationship between high BMI and amyloid accumulation, while other fat types showed no similar impact. The study highlights how managing visceral fat through lifestyle changes or medication could reduce Alzheimer's risk.
          Read More
          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·November 26, 2024·3 min read

          Alzheimer’s Drug Shrinks Brain Volume by Removing Amyloid Plaques

          Brain volume loss linked to new Alzheimer’s immunotherapies, such as lecanemab, is caused by the removal of amyloid plaques rather than neuronal damage. Researchers analyzed data from multiple trials and coined the term "amyloid-removal-related pseudo-atrophy" (ARPA) to describe this phenomenon.
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          This shows a pregnant woman.
          FeaturedGeneticsNeurologyNeuroscience
          ·November 21, 2024·5 min read

          Maternal Inflammation May Shape Offspring’s Alzheimer’s Risk

          Maternal immune activity during pregnancy influences memory circuitry in offspring, with sex-specific effects extending into midlife. Elevated immune markers like IL-6 and TNF-a in mothers were linked to adverse brain activity in memory regions, particularly in postmenopausal women, and lower cognitive performance in children.
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          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·November 20, 2024·3 min read

          Earpiece Tech Detects Early Alzheimer’s Through Eye Movement Signals

          Researchers are exploring how earpiece microphones, or "hearables," could detect early signs of Alzheimer’s disease by monitoring subtle eye movement changes. Alzheimer’s impacts motor and cognitive functions, with slowed or delayed eye movements (saccades) being an early indicator.
          Read More
          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·November 19, 2024·5 min read

          Early-Onset Diabetes Linked to Increased Dementia Risk

          New research reveals that individuals diagnosed with type 2 diabetes at a younger age face a higher risk of developing dementia, particularly those with obesity. The study found that for each year earlier type 2 diabetes is diagnosed, dementia risk increases by 1.9%.
          Read More
          This shows a researcher holding a card with blood on it, a brain is in the background.
          FeaturedNeurologyNeuroscience
          ·November 18, 2024·3 min read

          Finger-Prick Test Brings Alzheimer’s Detection Closer to Everyone

          A new Alzheimer’s test collects just a few drops of blood from a finger prick, which can be mailed to a lab for analysis. The test measures biomarkers like pTau217 and has shown similar accuracy to traditional venous blood sampling.
          Read More
          This shows a brain.
          FeaturedGeneticsNeurologyNeuroscience
          ·November 18, 2024·4 min read

          Unique Brain Plaques Linked to Alzheimer’s Mutation Decoded

          Researchers have identified the structure of amyloid beta fibrils linked to a rare inherited form of Alzheimer’s disease caused by the Arctic mutation. Using cryo-electron microscopy and NMR, they revealed a W-shaped fibril structure that explains the formation of cottonwool plaques—large, spherical brain structures unique to this mutation.
          Read More
          This shows a brain.
          FeaturedGeneticsNeurologyNeuroscience
          ·November 16, 2024·8 min read

          Alzheimer’s Linked to Key Proteins via Cerebrospinal Fluid Analysis

          Using cerebrospinal fluid from living patients, researchers have identified specific proteins and genetic pathways involved in the development and progression of Alzheimer’s disease. This proteomic analysis revealed 38 proteins likely to play causal roles in Alzheimer’s, 15 of which are potential drug targets.
          Read More
          This shows an older lady.
          FeaturedNeurologyNeuroscience
          ·November 12, 2024·5 min read

          Frailty Boosts Dementia Risk

          Frailty is a strong predictor of dementia risk, with risk increasing by 40% with each 4-5 additional age-related health conditions. This connection between frailty and dementia suggests that frailty may not simply result from undetected dementia but actively contributes to its onset.
          Read More
          This shows a neuron.
          FeaturedNeurologyNeuroscience
          ·November 11, 2024·6 min read

          Fluctuating Cholesterol Linked to Higher Dementia Risk

          Older adults with significant fluctuations in cholesterol levels are at increased risk for dementia and cognitive decline, even without medication changes. Researchers studied nearly 10,000 older adults, tracking their cholesterol levels and cognitive function over six years. High variability in total and LDL ("bad") cholesterol was associated with a 60% increase in dementia and 23% increase in cognitive decline.
          Read More
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          This shows a brain made of food.

          Ultra-Processed Foods Erodes Visual Attention

          This shows a depressed woman and thought bubbles.

          Why Feeling Good is Harder than Not Feeling Bad

          This shows an astrocyte.

          Astrocytes Identified as Key Target for Treating Fragile X Syndrome

          This shows a brain.

          Liver Talks to the Brain to Control Appetite

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