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Aging

Featured Genetics Neuroscience

·May 14, 2019·8 min read

Blocking protein curbs memory loss in old mice

Blocking VCAM1 increased neurogenesis, and reduced microglia reactivity in the hippocampus of older mice.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 9, 2019·3 min read

Anger more harmful to health of older adults than sadness

Experiencing daily anger increases inflammation and raises the risk of developing chronic illnesses, such as heart disease and cancer, in those aged 80 and over.

This flow diagram shows the link between mitochondria, health and aging

Featured Neuroscience

·May 8, 2019·2 min read

Mitochondrial function may explain link between intelligence, health and aging

Mitochondrial function may help explain the link between intelligence, general health and aging.

This shows an older couple taking a stroll in the park

Featured Neuroscience Open Neuroscience Articles Psychology

·May 4, 2019·3 min read

Mental well-being predicts leisure time physical activity in midlife

The quality of mental well-being one experiences at age 42 may be a strong predictor of time spent pursuing physical activities at age 50.

Featured Genetics Neurology Neuroscience

·May 1, 2019·5 min read

Restoring brain function in mice with symptoms of Alzheimer’s disease

Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.

This shows someone holding an old person's hands

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 30, 2019·5 min read

When is Alzheimer’s not Alzheimer’s? Researchers characterize a different form of dementia

LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone.

Featured Neurology Neuroscience

·April 30, 2019·3 min read

Poor sense of smell associated with nearly 50% higher risk for death in 10 years

Poor olfaction is correlated with higher long-term mortality in older adults, particularly in those with good health at baseline. Dementia, Parkinson's disease and weight loss may be possible drivers for the higher mortality rates, but around 70% of cases are unexplained.

Featured Neuroscience Psychology

·April 26, 2019·4 min read

Creativity is not just for the young

Conceptual Nobel laureates reach their peak during their mid-twenties, while experimentally innovative laureates peak in their mid-50s.

This shows two older ladies riding bikes

Featured Neurology Neuroscience

·April 25, 2019·3 min read

Exercise activates memory neural networks in older adults

Acute exercise in older adults has a positive impact on brain regions associated with memory and recall. Older adults who engaged in acute exercise had greater activation in the temporal gyrus, fusiform gyrus and hippocampus, resulting in increased semantic memory activation.

Featured Neurology Neuroscience

·April 23, 2019·6 min read

More evidence that blood tests can detect the risk of Alzheimer’s

Neurofilament light protein in plasma may be a noninvasive biomarker for neurodegeneration associated with Alzheimer's disease.

This shows two older ladies walking in a park

Featured Neuroscience Open Neuroscience Articles

·April 19, 2019·4 min read

Light, physical activity reduces brain aging

Light physical activity has positive benefits for brain health as we age. Spending an hour participating in light intensity physical activity was associated with the equivalent of 1.1 years less brain aging. Every additional hour spent exercising was linked to higher brain volume.

Featured Neurology Neuroscience

·April 17, 2019·4 min read

Brain stimulation reverses age-related memory loss

Transcranial magnetic stimulation applied to the parietal lobe improves the function of brain areas important for memory which are disrupted by aging. The study reports TMS helps improve memory in older adults experiencing memory loss to the level of younger adults.