FeaturedGeneticsNeurosciencePsychology·July 27, 2022·3 min readThe Role of Genetic Variants on Psychedelics’ Therapeutic EffectsGenetic variants of the 5-HT2A serotonin receptor may explain why some respond to psychedelic therapies for the treatment of mental health disorders while others don't.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·March 16, 2022·3 min readLargest Ever Psychedelics Study Maps Changes of Conscious Awareness to Neurotransmitter SystemsStudy reveals how psychedelic drug-induced changes in subjective awareness are rooted in specific neurotransmitter systems.Read More
AutismFeaturedNeurosciencePsychology·January 26, 2021·5 min readLSD May Offer Viable Treatment for Certain Mental DisordersLSD increases social behaviors by activating 5-HTPA serotonin receptors and AMPA receptors in the prefrontal cortex, and the mTORC1 protein. Activating all three factors promoted social interactions. The findings suggest supervised LSD microdosing may help alleviate some of the social problems associated with ASD and other mental health disorders that impact social behaviors.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·September 17, 2020·6 min readHow Psychedelics Bind to Key Serotonin ReceptorResearchers have uncovered the structure of psychedelic compounds when they actively bind to the 5-HT2A serotonin receptor on the surface of brain cells. The discovery could lead to the exploration of more precise compounds that offer the therapeutic effects of psychedelics for mental health disorders, but without the hallucinations.Read More
FeaturedNeurosciencePsychology·February 1, 2019·4 min readHyperactive Neurons May Be to Blame When Antidepressants Don’t WorkResearchers shed new light on why some people may not respond to antidepressants for major depressive disorder. The study reports, neurons in the brains of some with MDD may become hyperactive in the presence of SSRIs.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·October 26, 2018·4 min readHow LSD Changes PerceptionResearchers report LSD triggers a reduction in functional connection between areas of the brain that govern cognitive processes, while increasing connectivity in brain networks associated with sensory functions.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·June 12, 2018·4 min readKetamine and Psychedelic Drugs Change Structure of NeuronsA new study reveals psychedelics increase dendrites, dendritic spines and synapses, while ketamine may promote neuroplasticity. The findings could help develop new treatments for anxiety, depression and other related disorders.Read More
FeaturedOpen Neuroscience ArticlesPsychology·July 30, 2017·5 min readFaster Acting Antidepressants May Finally Be Within ReachResearchers explain how SSRI antidepressants initiate action by targeting a specific type of nerve cells. Findings may lead to the development of faster acting antidepressants.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·January 27, 2017·5 min readStructure of LSD and Its Receptor Explains Its PotencyResearchers report the key why LSD hallucinations last so long is due to how it fits into serotonin receptors.Read More
FeaturedPsychology·February 3, 2016·4 min readAn Alternative Treatment Target For SchizophreniaA new study suggests that dysregulation in the way two G protein-coupled receptors talk to each other may be responsible for some symptoms of schizophrenia.Read More