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Can the effects of the ketogenic diet help prevent epilepsy after traumatic brain injury? Mouse study
Mimicking effects of the ketogenic diet with a drug called 2-DG reduced cell excitation and epileptic activity in mouse models of post-traumatic epilepsy. 2-DG may have the potential to restore network function following TBI, reducing the risk of epilepsy associated with head injuries. The findings may have positive implications for people who developed post-traumatic epilepsy, suggesting a change in diet could help alleviate some symptoms.