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β-amyloid

This shows the deposits of AB in the brain of a person with Alzheimer's disease.

Featured Neurology

·June 1, 2015·6 min read

Sleep Deficit Linked to Accumulation of Alzheimer’s Protein and Memory Loss

A new study reports on a link between lack of restorative sleep and an accumulation of amyloid beta.

This illustration shows an open skull exposing the brain of a sleeping man.

Featured Neurology

·October 21, 2013·3 min read

Shorter Sleep Duration and Poorer Sleep Quality Linked to Alzheimer’s Disease Biomarker

Shorter periods of sleep and poorer quality of sleep are associated with greater buildup of beta anyloid, a new study reports.

The image shows role of autophagy in Aβ secretion from neurons.

Featured Neurology Open Neuroscience Articles

·October 3, 2013·2 min read

Cell Auto Cleaning Mechanism Mediates the Formation of Plaques in Alzheimer’s

Using transgenic mice, researchers find a lack of autophagy in neurons prevents the secretion of amyloid beta and the formation of β-amyloid plaques in the brain.

Featured Neuroscience

·June 24, 2013·4 min read

NMR Advance Brings Proteins into the Open

Researchers combine data from four different NMR techniques to observe chaperone GroEL capture a disordered beta-amyloid protein.

The image shows 3 diagrams of beta amyloid plaque formations.

Featured Neurology

·February 27, 2013·2 min read

Researchers Identify Possible Treatment Window for Memory Problems

A new study identifies a potential treatment window of several years for plaques in the brain considered to cause memory loss in diseases such as Alzheimer's.

The image shows a chart of the activation and antagonists of NMDA receptors.

Electrophysiology Featured Neuroscience

·February 19, 2013·2 min read

Rewriting a Receptor’s Role

Researchers upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons. The study describes how a compound linked to Alzheimer's disease impacts NMDA receptors and weakens synaptic connections between brain cells.

Featured Neurology

·August 1, 2012·2 min read

Artificial Butter Flavoring Ingredient Linked to Key Alzheimer’s Disease Process

A new study raises concern about chronic exposure of workers in industry to a food flavoring ingredient used to produce the distinctive buttery flavor and aroma of microwave popcorn, margarines, snack foods, candy, baked goods, pet foods and other products. It found evidence that the ingredient, diacetyl (DA), intensifies the damaging effects of an abnormal brain protein linked to Alzheimer’s disease.

Featured Neurology Neuroscience

·December 10, 2011·2 min read

Researchers Design Alzheimer’s Antibodies

A Surprisingly Simple Method To Target Harmful Proteins Researchers at Rensselaer Polytechnic Institute have developed a new method to design...

Neurology

·March 29, 2011·2 min read

Indications of Alzheimer’s disease may be evident decades before first signs of cognitive impairment

Researchers at Mount Sinai School of Medicine have found that patients with Alzheimer's disease have lower glucose utilization in the brain than those with normal cognitive function, and that those decreased levels may be detectable approximately 20 years prior to the first symptoms of Alzheimer's disease.