Summary: Contrary to popular belief, speech and singing use overlapping brain circuits, primarily located in the left hemisphere.
This discovery challenges the 50-year notion that the right hemisphere supports the singing ability in aphasia patients. The study found that the ability to produce sung words is tied to the left hemisphere’s language network.
These insights will pave the way for more personalized rehabilitation for aphasia patients.
Speech and singing abilities are both primarily connected to the left hemisphere’s language network.
Production of sung words is tied to the ventral stream, responsible for understanding speech.
Observations provide a deeper understanding of the evolution and overlap of speech and singing.
Source: University of Helsinki
Unlike previously thought, speech production and singing are supported by the same circuitry in the brain. Observations in a new study can help develop increasingly effective rehabilitation methods for patients with aphasia.
The neural network related to speech is mostly located in the left cerebral hemisphere, while singing has been primarily associated with the structures of both hemispheres. However, a new study indicates that the left hemisphere has a greater significance, including in terms of singing, than previously thought.
“According to a notion prevalent for more than 50 years, the potential preservation of singing ability in aphasia is based on the fact that the right hemisphere of the brain offers, as it were, a detour to expressing sung words,” says Doctoral Researcher Anni Pitkäniemi from the University of Helsinki.
This theory has also served as a basis for the development of singing-based rehabilitation strategies for patients with aphasia, or difficulty producing speech due to cerebrovascular disease.
However, a recently published study carried out by the Cognitive Brain Research Unit at the University of Helsinki found that, contrary to the researchers’ expectations, the ability to produce words by singing was associated not with the structures of the right hemisphere, but, as with speech, with the language network of the left hemisphere.
Both shared and distinct neural connections
Another key finding in the study was that, while the results indicate that the production of speech and singing are centrally linked to the language network of the brain, they are partially dispersed into distinct circuits under that network.
In fact, it was found that the production of sung words was linked to a specific part of the language network, the ventral stream associated with understanding speech.
In contrast, fluent speech was connected in patients with aphasia not only with what is known as the dorsal stream of the left hemisphere, associated with speech production, but also with other connections.
These include the above-mentioned ventral stream as well as pathways entirely outside the language network, which are more commonly associated with information processing and motor functions in the brain.
“The scale of the network demonstrates the complexity of conversation-level speech,” Pitkäniemi points out.
“The observation also now explains why the ability to produce familiar lyrics is preserved only in certain patients,” she adds. The extent of damage within the language network, she further remarks, has the largest effect on this.
According to Pitkäniemi, the structures of the right hemisphere considered central to singing are likely to play a more important role in other significant factors associated with singing, including the production of melody and rhythm.
Towards increasingly personalised rehabilitation
For centuries, researchers have been interested in the relationship between music and language.
“There are cases in research literature dating back to the eighteenth century of persons with stroke losing their ability to speak due to aphasia, while unexpectedly retaining the ability to sing the words of familiar songs fluently,” Pitkäniemi says.
Next, the researchers at the University of Helsinki intend to investigate which brain networks are connected, for example, to learning new songs or producing melody and rhythm. The goal is to find methods based on singing for rehabilitating people with aphasia, which could be applied in an increasingly personalised and effective manner.
“The findings of the recently published study can already help define biological markers that could be useful, for example, in assessing the effectiveness of treatment or rehabilitation,” Pitkäniemi muses.
“The findings also provide indications of the at least partly parallel development of speech and singing, which is interesting from the perspective of evolutionary neuroscience,” she adds.
Hodological organization of spoken language production and singing in the human brain
Theories expounding the neural relationship between speech and singing range from sharing neural circuitry, to relying on opposite hemispheres. Yet, hodological studies exploring their shared and distinct neural networks remain scarce.
In this study, we combine a white matter connectometry approach together with comprehensive and naturalistic appraisal of verbal expression during spoken language production and singing in a sample of individuals with post-stroke aphasia.
Our results reveal that both spoken language production and singing are mainly supported by the left hemisphere language network and projection pathways.
However, while spoken language production mostly engaged dorsal and ventral streams of speech processing, singing was associated primarily with the left ventral stream.
These findings provide evidence that speech and singing share core neuronal circuitry within the left hemisphere, while distinct ventral stream contributions explain frequently observed dissociations in aphasia.
Moreover, the results suggest prerequisite biomarkers for successful singing-based therapeutic interventions.