Summary: Are you finding it hard to find hand sanitizers in the wake of COVID-19? The WHO has provided a recommended formula to make your own hand disinfectants that can kill the SARS-CoV-2 virus within 30 seconds.
Source: RUB
When used correctly, both alcohol-based hand disinfectants recommended by the World Health Organization (WHO) are effective against the novel coronavirus Sars-Cov-2, as confirmed by an international research team headed by Professor Stephanie Pfänder from the Department of Molecular and Medical Virology at Ruhr-Universität Bochum (RUB). The journal Emerging Infectious Diseases published the relevant article in its online edition on 13 April 2020.
30 seconds for disinfection
The researchers exposed Sars-Cov-2 viruses for 30 seconds to the WHO-recommended disinfectant formulations. “This time frame was chosen based on recommendations for hand disinfectants,” says Stephanie Pfänder.
Subsequently, the team tested the viruses in cell culture assays and analysed how many viruses remained infectious. “We showed that both WHO-recommended formulations sufficiently inactivate the virus after 30 seconds,” as Stephanie Pfänder sums up the results. Plus, this does not merely apply to the WHO solutions; rather, their main components, the alcohols ethanol and isopropanol, also showed adequate inactivation of the virus.
WHO-recommended formulations
The disinfectant recommended by the WHO consists of 80 volume percent ethanol, 1.45 volume percent glycerine and 0.125 volume percent hydrogen peroxide. Disinfectant II consists of 75 volume percent isopropanol, 1.45 volume percent glycerine and 0.125 volume percent hydrogen peroxide.
German Pharmacies allowed to sell WHO-II formulation
Following the amendments to the German Drug Law by the German government on Wednesday, March 4, 2020, that will remain in effect for six months, the formulation WHO II, which is based on isopropanol, has been approved for this period. As a result, pharmacies are permitted to produce and sell this formulation in order to alleviate the current shortage of disinfectants.
About this coronavirus research article
Source:
RUB
Media Contacts:
Meike Drießen – RUB
Image Source:
The image is in the public domain.
Original Research: Open access
“Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols”. by Annika Kratzel, Daniel Todt, Philip V’kovski, Silvio Steiner, Mitra Gultom, Tran Thi Nhu Thao, Nadine Ebert, Melle Holwerda, Jörg Steinmann, Daniela Niemeyer, Ronald Dijkman, Günter Kampf, Christian Drosten, Eike Steinmann, Volker Thiel, and Stephanie Pfaender.
Emerging Infectious Diseases doi:10.3201/eid2607.200915.
Abstract
Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols
Infection control instructions call for use of alcohol-based hand rub solutions to inactivate severe acute respiratory syndrome coronavirus 2. We determined the virucidal activity of World Health Organization–recommended hand rub formulations, at full strength and multiple dilutions, and of the active ingredients. All disinfectants demonstrated efficient virus inactivation.
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