Researchers use induced pluripotent stem cells to advance disease-in-a-dish modeling of ataxia telangiectasia, a rare genetic disorder associated with progressive loss of function in the cerebellum. Their discovery shows the positive effects of drugs that may lead to effective new treatments for the neurodegenerative disease.
Researchers discover significant sex-based brain anatomy differences between males and females with dyslexia.
Using neuroimaging, researchers discovered glutamate levels are abnormally high in people with restless leg syndrome. The higher the level of glutamate in patients with RLS, the less sleep they were able to get.
A population based study which looked at patients newly diagnosed with MS discovered African-Americans had a 47% increased risk of developing the disease compared with Caucasians. However, Hispanic and Asian people had a 58 and 80% lower risk.
Researchers have identified the Ggamma13 protein is critical for the ability for mammals to detect odors. “Knockout” mice which lacked this protein were functionally anosmic, unable to smell. The study could provide insight into possible underlying causes of certain smell disorders in humans.
A new treatment for ALS, which uses a technique that turns off the mutated SOD1 gene, has passed an early phase clinical trial for safety.
A new study supports p38α MAPK as a possible clinical target for treating central nervous system disorders associated with uncontrolled brain inflammation, including TBI.
As Alzheimer’s disease progresses, microglial cells lose two important biological functions affecting their ability to remove cell fragments and motility towards acute lesions.