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Schizophrenia

Featured Genetics Neuroscience Psychology

·October 9, 2019·6 min read

Scientists reverse core symptom of schizophrenia in adult mice

Neuronal branches in SETD1A deficient mice are shorter and stunted. Switching off another gene, LSD1, nullifies the harmful effects of SETD1A on neuron and axon growth. After inhibiting LSD1, SETD1A deficient mice showed improved memory and axon growth. Inhibiting LSD1 not only acted on memory deficits linked to schizophrenia but also acted on the underlying molecular mechanisms associated with axonal growth.

Featured Neuroscience Psychology

·October 4, 2019·3 min read

Promising steps towards hope for a treatment for schizophrenia

Mu-opioid receptor (MOR) levels are significantly reduced in the striatum in those with schizophrenia. A lack of MOR system stimulation contributes to negative feelings, such as a lack of motivation and anhedonia, associated with the condition. Increasing MOR levels could help to reduce some of the symptoms of schizophrenia.

Featured Neuroscience Open Neuroscience Articles Psychology

·October 2, 2019·4 min read

The propensity to hear ‘voices’ in Schizophrenia may be established by infancy

People with schizophrenia who experience auditory hallucinations have greater activation in specific areas of the auditory cortex in response to sound frequencies. The mapping of sound frequency in the auditory cortex is scrambled in those with schizophrenia, suggesting a disruption in the normal processes for organized sound representation in the brain. As the tonotopic map is established during infancy and remains stable throughout life, the findings suggest vulnerability for auditory hallucinations is linked to defects in the organization of the auditory system during infantile development. This precedes speech development and the onset of psychiatric symptoms.

This shows the outline of a brain with a where's waldo image inside

Electrophysiology Featured Neuroscience

·October 1, 2019·4 min read

Researcher records neurons to understand cognition

Neurons in the pre-supplementary motor area play a critical role in visual search.

Featured Neuroscience Psychology

·September 27, 2019·4 min read

Abused or neglected children are four times more likely to develop serious mental illness

Adults who were maltreated as children have an increased risk of being diagnosed with schizophrenia, psychosis, bipolar disorder, and anxiety than their peers who were not abused.

Featured Genetics Neuroscience Psychology

·September 23, 2019·4 min read

Gene regulators work together for oversized impact on schizophrenia risk

Using CRISPR to alter the expression of four schizophrenia implicated genes which harbor expression quantitative trait loci, researchers were able to mirror gene expression changes seen in postmortem brains of those suffering from three mental health disorders.

Featured Neurology Neuroscience Open Neuroscience Articles Psychology

·September 19, 2019·4 min read

Autoantibodies in pregnancy: A cause of behavioral disorders in the child?

Embryonic damage caused by autoantibodies is implicated in a range of behavioral and psychological disorders, including schizophrenia, autism, and ADHD.

Featured Neuroscience Open Neuroscience Articles Psychology

·September 17, 2019·4 min read

Large survey suggests schizophrenia less prevalent than textbooks say

A systematic review of medical literature reveals schizophrenia is overall less common than previously thought. Researchers say the 0.5% estimate for lifetime prevalence of schizophrenia, often reported in textbooks, is significantly overestimated. Additional findings from the review were that schizophrenia is more prevalent in developed countries than poorer countries, and immigrants have higher rates of schizophrenia diagnoses than native-born people.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·September 14, 2019·4 min read

Scientists identify gene as master regulator in schizophrenia

TCF4 may serve as a master regulator of a gene network dysregulated in schizophrenia at the early stages of neurodevelopment.

Featured Neuroscience Psychology

·September 13, 2019·2 min read

Dietary supplement may help with schizophrenia

The dietary supplement sarcosine taken in combination with antipsychotic medications may be beneficial for the treatment of schizophrenia.

Featured Neuroscience Psychology

·September 8, 2019·3 min read

Study locates brain areas for understanding metaphors in healthy and schizophrenic people

Patients with schizophrenia show increased brain activity in central areas of the brain, but lower activity in the temporal sulcus when hearing metaphors.