Using mouse models, researchers discover TSPO ligands can significantly decrease Alzheimer’s related symptoms and improve memory. The discovery could lead to preventative and new treatment options for Alzheimer’s disease.
Researchers discovered a novel molecular target for the design of drugs which could be safer and more effective for multiple sclerosis, as well as other disorders associated with the loss of white matter in the brain.
A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer’s disease in aged mice following short-term treatment.
Using a tiny dose of the leukemia drug nilotinib, researchers halt the accumulation of toxic proteins linked to Parkinson’s diseases in the brains of mice.
A new vaccine for Lyme disease, a neurological and physically debilitating tick borne disease, has proved promising and well tolerated by patients, according to researchers. The Lyme vaccine is shown to produce substantial antibodies against all targeted species of Borrelia, the causative agent of Lyme disease.
Researchers have successfully tested a new vaccine in primates to battle cocaine addiction. Using neuroimaging techniques, they demonstrated the vaccine prevents cocaine from reaching the brain and producing a dopamine induced high. Human trials could begin within the next year.
Researchers have discovered how cholinesterase inhibitors, a class of drug that prevents the breakdown of acetylcholine, could sharpen the brain’s performance in patients with Alzheimer’s disease.
Researchers have identified that the TR4 protein, which regulates a gene that produces ACTH, drives the formation of pituitary tumors in Cushing’s disease.
Scientists reported successful preclinical tests in rats of a new vaccine against heroin addiction. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, blocking relapse.
Targeting the nucleus accumbens by using deep brain stimulation could modify specific eating behaviors linked to weight changes and obesity, a new study suggests.