FeaturedNeuroscience·April 17, 2023·5 min readA Brain Model Learns to DriveA new AI model that mimics the neural architecture and connections of the hippocampus is able to alter its synaptic connections as it moves a car-like virtual robot.Read More
ElectrophysiologyFeaturedNeuroscience·April 16, 2023·4 min readLong-Term Use of Steroids Could Impair MemoryHippocampal activity was profoundly impaired in rodent models of long-term steroid exposure, leading to memory deficits.Read More
FeaturedNeurologyNeuroscience·April 11, 2023·4 min readScientists Enhance New Neurons to Restore Memory and Elevate Mood in Alzheimer’s DiseaseStimulating the Supramammilary nucleus in the hypothalamus enhanced adult-born neurons in the hippocampus of mouse models of Alzheimer's disease. These modified adult-born neurons restored both cognitive impairments and mood-related disorders associated with Alzheimer's in the mice.Read More
ElectrophysiologyFeaturedNeuroscience·April 11, 2023·2 min readKey Memory Receptors Are Located on InterneuronsInterneural α5-GABAARs play a critical physiological role in promoting spatial learning and serve as essential targets for the modulation of contextual memory.Read More
FeaturedNeurologyNeuroscience·April 6, 2023·4 min readActivating Adult-Born Neurons Through Deep Brain Stimulation Alleviates Alzheimer’s SymptomsDeep brain stimulation of newborn hippocampal neurons restored both cognitive and non-cognitive function in mouse models of Alzheimer's disease.Read More
FeaturedGeneticsNeuroscience·April 2, 2023·4 min readA Key Process in How the Brain Consolidates MemoriesResearchers have identified a molecular process involved in gene expression in neurons which appears to play a key role in memory consolidation.Read More
FeaturedNeuroscience·March 24, 2023·3 min readA New Full-Scale 3D Structural Model of the Human HippocampusResearchers have developed a new 3D, high-resolution model of the CA1 area of the human hippocampus.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·March 15, 2023·3 min readCharacterizing Abnormal Neural Networks in Dogs With AnxietyDogs with anxiety have stronger neural connections between the amygdala and other areas of the anxiety network in the brain compared to less anxious dogs.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·March 15, 2023·3 min readMemories Could Be Lost if Two Key Brain Regions Fail to Sync TogetherIf neural assemblies between the hippocampus and prefrontal cortex fail to sync together at the correct time, memories are lost.Read More
FeaturedGeneticsNeuroscience·March 8, 2023·4 min readHow Gene Expression Controls Synaptic Plasticity in the Aging Human BrainM1 muscarinic acetylcholine receptor (mAChR) dependent LTP and LTD share a common AMPA trafficking pathway. Either the upregulation of neurotransmitter receptor genes or suppression of the downregulation could improve synaptic dysfunction associated with age-related neurodegeneration. The findings could assist in the creation of new therapies for Alzheimer's disease that target synaptic plasticity.Read More
FeaturedNeuroscience·February 28, 2023·3 min readStudying Brain Oscillations to Understand What Makes a Memory StickMemory formation requires higher-frequency ripples in the hippocampus and lower-frequency ripples in the parietal cortex. However, to make a memory stick, coordinated high-frequency ripples between the hippocampus and parietal cortex are required.Read More
FeaturedNeuroscience·February 14, 2023·6 min readMysterious Brain Activity in Mice Watching a Movie Could Help Tackle Alzheimer’s and Improve AITracking hippocampal neurons in mice as they watched a movie revealed novel ways to improve artificial intelligence and track neurological disorders associated with memory and learning deficits.Read More