Alzheimer’s Drug Discovery: Looking Under the Right ROCK
Researchers have discovered a potential drug which can force BACE into different parts of a cell, reducing its ability to produce amyloid beta.
Human Stem Cells Predict Efficacy of Alzheimer Drugs
Researchers transform iPSCs into neurons to test the efficacy of drugs to treat Alzheimer’s disease.
Study Treats Alzheimer’s by Delivering Protein Across Blood-Brain Barrier
Researchers discover a way to traverse the blood-brain barrier and retinal-blood barrier to deliver a molecule which degrades the main component of Alzheimer’s plaques.
Study Reveals How Variant Forms of APOE Protein Impact Risk of Alzheimer’s Disease
A new study reports even low levels of APOE4 can increase beta-amyloid plaques in the brain and neuronal damage in mouse models of Alzheimer’s disease. However, introducing APOE2 can reduce amyloid deposits and other associated damage.
New Review Finds Statin Use Not Linked to a Decline in Cognitive Function
According to a comprehensive systematic review, available evidence does not support an association between statins and cognitive decline.
Understanding a Protein’s Role in Familial Alzheimer’s Disease
Researchers use a novel genomic approach to better understand genetic mutations associated with familial Alzheimer’s disease.
High Blood Pressure in Middle Age Versus Old Age May Better Predict Memory Loss
According to a new study, middle aged people with high pulse pressure are more likely to have biomarkers for Alzheimer’s disease in their spinal fluid than those with lower pulse pressure.
New Research May Improve Early Detection of Dementia
Analyzing scores obtained from cognitive tests, researchers believe they have developed a model which could detect early signs of dementia.
New Method Predicts Time from Alzheimer’s Onset to Nursing Home and Death
Researchers have clinically validated a new method to predict the time it takes to enter full-time care in nursing homes or death for patients with Alzheimer’s disease.
Speaking a Second Language May Delay Dementia
Researchers discover later onset of dementia in people who speak more than one language.
