Summary: Children who experience frequent nightmares at age 11 are twice as likely to develop symptoms of cognitive impairment, and seven times more likely to develop Parkinson’s disease by age 50.
Source: The Conversation
Can children’s dreams foretell events that will happen nearly 40 years into the future? Yes, according to the results of my latest study published in The Lancet’s eClinicalMedicine journal.
More specifically, it showed that children who experience regular bad dreams and nightmares between the ages of seven and 11, may be nearly twice as likely to develop cognitive impairment (the core feature of dementia) by the time they reach age 50. And they may be up to seven times more likely to be diagnosed with Parkinson’s disease by age 50.
For some background to these startling findings, in 2022 I discovered that middle-aged and older adults who experience frequent bad dreams and nightmares could be more than twice as likely to develop dementia or Parkinson’s in the future.
Given that a large proportion of people who experience regular nightmares as adults also report having had regular nightmares when they were children, this made me wonder whether having lots of bad dreams during childhood might predict the development of dementia or Parkinson’s disease later in life.
To find out, I used data from the well-known 1958 British birth cohort study, which follows the lives of all children born in England, Scotland and Wales during the week of March 3–9, 1958.
When the children were aged seven (1965) and 11 (1969), their mothers answered a range of questions about their health, including whether they had experienced bad dreams in the previous three months (yes/no).
I grouped the 6,991 children based on how regularly they experienced bad dreams at ages seven and 11: “never”, “occasional”, or “persistent”. I then used statistical software to determine whether the children with more regular bad dreams were more likely to develop cognitive impairment or be diagnosed with Parkinson’s by the time they turned 50 (2008).
The results were clear. The more regularly the children experienced bad dreams, the more likely they were to develop cognitive impairment or be diagnosed with Parkinson’s disease.
Remarkably, compared with children who never had bad dreams, those who had persistent bad dreams were 76% more likely to develop cognitive impairment and were 640% more likely to develop Parkinson’s. This pattern was similar for both boys and girls.
These results suggest that having regular bad dreams and nightmares during childhood may increase the risk of developing progressive brain diseases like dementia or Parkinson’s disease later in life. They also raise the intriguing possibility that reducing bad dream frequency during early life could be an early opportunity to prevent both conditions.
Further studies will be needed to confirm whether bad dreams and nightmares truly cause these conditions.
The frequency with which we experience nightmares as children is to a large degree determined by our genetics. And one gene known to increase our risk of having regular nightmares (PTPRJ) is also linked to increased risk of developing Alzheimer’s disease in old age. So it’s possible that nightmares and progressive brain diseases are both caused by a shared set of genes.
My hunch is that both theories could be true. That is, nightmares and progressive brain diseases are linked by shared genetics, as well as through nightmares directly causing brain diseases by disrupting the brain-restoring elements of sleep.
Don’t be alarmed
Although these findings sound alarming, put in their proper context, they shouldn’t be. Of the roughly 7,000 children included in my study, only 268 (4%) had persistent bad dreams according to their mothers. Among these children, only 17 had developed cognitive impairment or Parkinson’s disease by age 50 (6%).
So it is likely that the vast majority of people who have persistent bad dreams in childhood are not going to develop early-onset dementia or Parkinson’s.
However, the risk of developing progressive brain diseases increases substantially in old age. Being aware that bad dreams in childhood may signal a higher risk of dementia or Parkinson’s later in life suggests that there could be a window of opportunity to implement simple strategies to lower those risks. And for young people with frequent distressing dreams that persist over time, getting help for nightmares might be one such strategy.
The next step for my research is to use electroencephalography (a technique to measure brainwaves) to look at the biological reasons for bad dreams and nightmares in children.
In the longer term, the aim will be to use this knowledge to develop new treatments for all people troubled by bad dreams and nightmares. The ultimate goal is to improve their sleep quality and mental health and reduce their chance of developing dementia or Parkinson’s disease later in life.
About this sleep and neurodegeneration research news
Author: Abidemi Otaiku
Source: The Conversation
Contact: Abidemi Otaiku – The Conversation
Image: The image is in the public domain
Original Research: Open access.
“Distressing dreams in childhood and risk of cognitive impairment or Parkinson’s disease in adulthood: a national birth cohort study” by Abidemi Otaiku. eClinical Medicine
Abstract
Distressing dreams in childhood and risk of cognitive impairment or Parkinson’s disease in adulthood: a national birth cohort study
Background
Distressing dreams in middle-aged and older adults have been associated with an increased risk of developing cognitive impairment (including dementia) and Parkinson’s disease (PD). Whether distressing dreams in younger people might be associated with an increased risk of developing these conditions is unknown. This study investigated the association between distressing dreams in childhood and the risk of developing cognitive impairment or PD by age 50.
Methods
Data from the 1958 British Birth Cohort Study – a prospective birth cohort which included all people born in Britain during a single week in 1958, were used in this longitudinal analysis. Information on distressing dreams were obtained prospectively from the children’s mothers at ages 7 (1965) and 11 (1969). Cognitive impairment and PD at age 50 (2008) were determined by cognitive assessment and doctor-diagnosis respectively. The association between distressing dreams at ages 7 and 11 (no time point, 1 time point, 2 time points) and cognitive impairment or PD at age 50, was evaluated using multivariable Firth logistic regression, with adjustment for potential confounders.
Findings
Among 6991 children (50.6% female) with follow-up available at age 50, 267 (3.8%) developed cognitive impairment or PD. After adjustment for all covariates, having more regular distressing dreams during childhood was linearly and statistically significantly associated with higher risk of developing cognitive impairment or PD by age 50 (P for trend = 0.037). Compared with children who never had distressing dreams (no time point), children who had persistent distressing dreams (2 time points) had an 85% increased risk of developing cognitive impairment or PD by age 50 (adjusted odds ratio = 1.85; 95% CI: 1.10, 3.11).
Interpretation
Having persistent distressing dreams during childhood may be associated with an increased risk of developing cognitive impairment or PD in adulthood. Future studies are needed to confirm these findings and to determine whether treating distressing dreams during early life may lower the risk of dementia and PD.
Funding
The study received no external funding.
