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Autism

Research articles covering work related to austism spectrum disorders are provided below.

Autism Featured Genetics Neurology Neuroscience

·March 7, 2025·4 min read

Genetic Variant in ITSN1 Linked to Higher Parkinson’s and ASD Risk

A new study has identified genetic variants in the ITSN1 gene that significantly increase the risk of developing Parkinson’s disease. Researchers analyzed nearly 500,000 genetic profiles and found that individuals carrying ITSN1 variants face up to a tenfold higher risk of Parkinson’s.

Autism Featured Neuroscience Psychology

·March 3, 2025·8 min read

Maternal Diet Influences ADHD and Autism Risk

A large study analyzing over 60,000 mother-child pairs found that a Western diet during pregnancy—high in fat, sugar, and processed foods—was associated with a significantly increased risk of ADHD and autism in children. Even small shifts toward a Western diet correlated with a 66% higher risk of ADHD and a 122% higher risk of autism.

Autism Featured Genetics Neuroscience

·January 31, 2025·7 min read

Genetics, Not Maternal Sickness, Drives Autism Risk

A large study analyzing over 1.1 million pregnancies found no strong evidence that maternal health conditions during pregnancy cause autism. Instead, nearly all previously reported associations between maternal diagnoses and autism could be explained by genetic or environmental factors.

Autism Brain Cancer Featured Genetics Neuroscience

·January 9, 2025·8 min read

Youthful Brain Stem Cells Linked to Autism and Brain Cancer

Researchers have identified a unique stem cell in the young brain capable of maturing into multiple cell types, potentially explaining the origins of autism and glioblastoma. These stem cells show gene expression patterns that regulate early brain development and, when disrupted, could lead to neurological conditions.

Autism Featured Genetics Neuroscience

·January 8, 2025·5 min read

Single Gene Links Autism, Epilepsy via Brain Circuit Development

The gene neuropilin2 regulates inhibitory neuron migration and excitatory neuron connections, essential for balanced brain activity. A study revealed that deleting neuropilin2 disrupts inhibitory circuits, leading to autism-like behaviors and a higher seizure risk.

Autism Featured Neuroscience

·January 3, 2025·4 min read

Multilingualism Boosts Cognitive Skills in Children With Autism

Children in multilingual households, including those with autism, demonstrate stronger executive functions, such as inhibition, flexibility, and perspective-taking, compared to monolingual peers. Speaking multiple languages also reduces repetitive behaviors and improves communication, key challenges in autism.

Autism Featured Genetics Neuroscience

·December 27, 2024·5 min read

Lithium Restores Brain Function and Behavior in Autism

Lithium, a drug widely used for bipolar disorder, may also treat autism spectrum disorder (ASD), according to new research. The study found that lithium restored brain function and reduced behavioral symptoms in mice with Dyrk1a gene mutations, a known ASD risk factor.

Autism Featured Genetics Neuroscience

·December 16, 2024·6 min read

Protein Loss Triggers Molecular Changes Linked to Rett Syndrom

Researchers have uncovered how loss of the MeCP2 protein triggers early molecular changes leading to Rett syndrome, a severe neurological disorder. By studying adult mice, they demonstrated that MeCP2 loss disrupts gene expression well before measurable neurological deficits arise.

Autism Featured Neuroscience

·December 9, 2024·6 min read

Why Autistic Children View Faces Differently

Children with autism exhibit distinct eye movement patterns when viewing faces, particularly in the initial stages of visual processing. A new study found that autistic children are more likely to use an exploratory eye movement pattern, focusing on broader areas rather than immediately fixating on facial features. This behavior may be linked to reduced visual sensitivity to social cues and is associated with autism-related challenges in social communication.

Autism Featured Genetics Neuroscience Psychology

·December 5, 2024·6 min read

Gene Defect Linked Brain Size and Social Behavior in ASD, Schizophrenia

A new study reveals how genetic deficits, particularly in the Tbx1 gene, are linked to reduced brain volume and altered social behavior, findings relevant to autism and schizophrenia. Researchers observed smaller amygdala volumes in Tbx1-deficient mice, a brain region key to emotional regulation and social behavior. These mice displayed less interest in social interaction, relying more on non-social cues like bedding preferences.

Autism Featured Genetics Neuroscience

·December 5, 2024·7 min read

Missing Genetic Link Uncovered in Idiopathic Autism

Researchers have uncovered a molecular mechanism linking alterations in the neuronal protein CPEB4 to idiopathic autism, which accounts for 80% of autism cases without a clear genetic cause. The study reveals that the absence of a specific microexon in CPEB4 disrupts the dynamics of molecular condensates in neurons, affecting the regulation of genes crucial for brain development. This disruption can lead to reduced protein production, impairing neuronal growth and function.

Autism Featured Genetics Neuroscience Psychology

·November 21, 2024·4 min read

Immune System Gene Linked to Hyperactivity, ADHD and Autism

Researchers have uncovered a link between the immune gene regulator STAT1 and hyperactive behaviors in mice, offering new insights into neurodevelopmental disorders like autism and ADHD. STAT1, vital for infection response, also influences brain cell activity, particularly dopamine neurons involved in motivation and learning. In mice with prolonged STAT1 signaling, hyperactivity and reduced neural activity in key brain regions were observed. The study opens the door to targeting STAT1 for potential therapies to address neurobehavioral disorders.