Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.
A new algorithm uses neuroimaging data of amyloid levels in the brain and takes into account a person's age to determine when a person with genetic Alzheimer's risk factors, and with no signs of cognitive decline, will develop the disease.
Researchers have identified a new reward system in the brain. The study found long-range GABA neurons from the ventral tegmental area to the ventral nucleus accumbens shell are engaged in reward and reinforcement behaviors. This GABAergic projection inhibits cholinergic interneurons.
Chikungunya, and other mosquito-borne alphaviruses are known to trigger brain infections and arthritis in those who contract the infections. Researchers have identified two antibodies that protect animals from diseases caused by alphaviruses. The findings could pave the way to new treatments and a universal vaccine for alphaviruses.
A study spanning 17 years has found children born and raised in poverty had smaller subcortical brain regions, including the hippocampus, caudate, putamen, and thalamus. These brain areas also showed less growth over time.