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vision loss

Featured Genetics Neuroscience Visual Neuroscience

·October 16, 2025·6 min read

Scientists Identify New Gene Behind Hereditary Vision Loss

Researchers have identified a new genetic cause of hereditary optic atrophy—a condition that leads to gradual vision loss—by discovering a previously unknown mutation in the PPIB gene. This gene helps proteins fold properly and ensures healthy mitochondrial function, both of which are disrupted in affected individuals.

Featured Neuroscience Visual Neuroscience

·October 6, 2025·5 min read

Hidden Early Signs of Diabetic Blindness Revealed

Scientists have developed a powerful new imaging method that reveals how immune cells in the eye behave long before visible damage occurs in diabetic retinopathy. Using a combination of a head-fixation device, contact lenses, and a custom objective lens, researchers were able to capture live, high-resolution images of microglia activity in diabetic mice.

Featured Genetics Neuroscience Visual Neuroscience

·September 26, 2025·5 min read

mRNA Vaccine Targets Vision Loss in AMD

A new mRNA vaccine developed in Japan has been shown to suppress abnormal blood vessel growth in the retina of mice, offering hope for patients with age-related macular degeneration (AMD). Current treatments require repeated injections directly into the eye, but this vaccine can be delivered intramuscularly, making it less invasive and easier to administer.

Featured Genetics Neuroscience Visual Neuroscience

·September 23, 2025·4 min read

Human Stem Cell Transplants Boost Vision in Advanced Dry AMD

A new clinical trial suggests stem cell therapy may restore vision in people with advanced dry age-related macular degeneration, a disease that currently has no cure. Researchers transplanted retinal pigment epithelial stem cells, derived from adult postmortem eye tissue, into patients’ eyes.

Featured Neuroscience Visual Neuroscience

·July 21, 2025·6 min read

Youthful Blood Restores Aging Retina and Vision

Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function. Using heterochronic parabiosis and single-cell RNA sequencing, the study identified AdipoR1 and its downstream AMPK signaling as key drivers of retinal rejuvenation.

Featured Genetics Neuroscience Visual Neuroscience

·July 18, 2025·3 min read

Innovative Therapies Help Restore Vision Loss in Macular Degeneration

Age-related macular degeneration (AMD) remains a leading cause of vision loss, but new therapies are reshaping its treatment. Recently approved drugs, pegcetacoplan and avacincaptad pegol, target the complement system to slow dry AMD progression.

Featured Neuroscience Neuroscience Videos Visual Neuroscience

·July 7, 2025·5 min read

Retinal Cells Rewire to Preserve Vision in Degenerative Eye Disease

New research shows that retinal neurons can rewire to preserve vision in retinitis pigmentosa, a genetic disease causing blindness. Using mouse models, scientists found that rod bipolar cells adapt by forming functional connections with cone cells when their usual rod partners degenerate.

Featured Genetics Neuroscience Visual Neuroscience

·June 24, 2025·7 min read

Could This Molecule Prevent Vision Loss in AMD?

A new study reveals that increasing levels of apolipoprotein M (ApoM) may slow or prevent the progression of age-related macular degeneration (AMD), a major cause of blindness in older adults. Researchers found that low ApoM impairs cholesterol metabolism in the retina, contributing to inflammation and vision loss—especially in advanced forms like geographic atrophy.

Featured Neuroscience Visual Neuroscience

·May 15, 2025·6 min read

Eye Pressure May Trigger Irreversible Vision Loss

New research reveals how elevated eye pressure distorts blood vessels and disrupts oxygen delivery, potentially accelerating the progression of glaucoma, a leading cause of irreversible vision loss. Using advanced 3D modeling and fluorescent dyes, scientists found that even mild increases in eye pressure can restrict blood flow in the optic nerve region.

Featured Neuroscience Visual Neuroscience

·May 7, 2025·5 min read

Low Blood Sugar Triggers Retinal Damage, Vision Loss

New research reveals that hypoglycemia may worsen diabetic retinopathy by breaking down the blood-retinal barrier. In diabetic mice, low blood sugar increased levels of hypoxia-inducible factor (HIF), a protein linked to abnormal blood vessel growth and leakage.

Featured Neuroscience Visual Neuroscience

·April 22, 2025·4 min read

Rewiring Retinal Messages to Slow Vision Loss in AMD

Age-related macular degeneration (AMD), the leading cause of adult blindness, affects nearly half of Oklahomans over age 80. New research is uncovering how retinal cells communicate using microRNA and extracellular vesicles (EVs), with the goal of slowing AMD progression.

Featured Neuroscience Visual Neuroscience

·April 17, 2025·6 min read

Gold Nanoparticles Restore Vision in Macular Degeneration

A new study shows that gold nanoparticles injected into the retina can restore vision in mice with retinal degeneration, offering a less invasive alternative to current retinal prostheses. When activated by patterned infrared light, these nanoparticles stimulate retinal cells, bypassing damaged photoreceptors.