Novel experiences dampen previous memory representations in the hippocampus and prefrontal cortex, facilitating flexible strategy encoding in mice.
A circuit-specific gender difference in ventral hippocamps to nucleus accumbens (vHPC-NAc) neurons is dependent on testosterone and causes more susceptibility to stress in females.
Using optogenetics to stimulate different areas of the hippocampus has the ability to enhance or suppress memories in mice. The findings could have implications for suppressing memories associated with traumatic events in PTSD, and also in enhancing cognitive ability or improving memory for those with neurodegenerative diseases, in the future.
The gut microbiome contributes to depression-like behaviors and inflammation in the ventral hippocampus, according to a new rat study. Fecal transplants from rats with lower levels of Clostridia reduced depressive behaviors and inflammation in vulnerable rodents.
Researchers have identified neurons in the brains of rats that control future food intake by preserving memories of past meals. The findings suggest boosting meal memories could help to manage overeating and curb obesity.
A new study of the amygdala maps diverse and distinct, dynamic areas where feelings are assigned to experiences.
According to a new study, susceptibility to depression can be affected by tweaking specific gene networks.
New understanding about ketamine's antidepressant effect could lead to the development of new, safer and quicker ways to treat depression.