By adding a molecule that disrupts certain pathways in cells, researchers have discovered a new way to limit inflammation from adjuvants in vaccinations. Read More
Using computational methods, researchers created artificial proteins that triggered immune responses and produced infection specific antibodies. The findings indicate it will be possible to design vaccines that contain artificial antibodies, expediting the process of vaccine development. Read More
Researchers report they have identified a vaccine candidate for COVID-19 and are working towards phase one clinical testing. A chimpanzee adenovirus vaccine vector was chosen as the most suitable vaccine technology for SARS-CoV-2 as it can generate a stronger immune response in one dose and is not a replicating virus. Read More
Researchers are making progress in developing potential vaccines for coronavirus infections. While a vaccine for COVID-19 might be over a year away from market, researchers are looking ahead to attempt to prevent future outbreaks. Read More
Clinical trials for a preventative treatment for dementia was successful in mouse models. Researchers say human trials will begin in two years. Read More
A newly developed vaccine for meningitis and other bloodstream infections caused by the meningococcal group B bacteria will allow for the immunization of younger children. The new vaccine also addresses several limitations of the current meningitis vaccine. Read More
Researchers have engineered a vaccine using virus-like particles that target Tau tangles in mouse models of Alzheimer's disease. Following the administration of the vaccine, the mice developed antibodies that cleared tau proteins, with the response lasting for a month. The mice also showed improvements in memory based tests and had less brain shrinkage than their peers who did not receive the vaccine. This suggests the vaccine prevented apoptosis. Researchers hope to move the vaccine to human clinical trials in the future. Read More
From anti-vaccine rhetoric to the over-prescription of antibiotics, researchers suggest we should try to work together to improve public health, rather than socially shun those who ignore scientific evidence. Read More
Researchers report one method to help combat anti-vaccine information and reduce vaccine hesitancy is to introduce those with negative views about immunizations to someone who has suffered a vaccine-preventable disease. The study reports 70% of students who were exposed to someone with a vaccine-preventable disease moved from vaccine hesitancy to pro-vaccine. Overall, 75% of those who were anti-vaccine increased their vaccine attitude scores, with 50% moving to a pro-vaccine stance. Read More
Current vaccination policies are not sufficient to eliminate measles or prevent against future epidemics in the developed world, researchers report. Introducing compulsory vaccinations before entering school would allow the US, UK and Ireland to reach stable levels of herd immunity in the next ten years, thus helping to avoid future epidemics of the most lethal vaccine-preventable disease. Read More
Researchers will present a systematic review of scientific evidence for, and against causal associations for 47 proposed adverse events following immunizations at PAS 2019. The review found that, for 12 of the 47 AEFIs in the study, a causal relationship has been established with at least one vaccine. With the exception of deltoid bursitis, where a vaccine is administered incorrectly, causing pain to the arm, the adverse reactions are very rare. For the other 35 AEFis, the evidence does not support a causal relationship between conditions, such as ASD, asthma, diabetes, multiple sclerosis or SIDs, and vaccinations. Read More
A new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial. Read More
