Researchers identified two genes that respond to age-related iron accumulation in the substantia nigra. Knockdown of these genes results in severely impairing the cellular tolerance for iron toxicity.
The LSM12-EPAC1 pathway is an important suppressor of the NCT-related pathologies associated with ALS and FTD.
Researchers report a targeted removal of senescent cells could delay the onset of age related pathologies.
Researchers reveal a possible new method to help treat Alzheimer's disease.